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- Title
Usefulness of fluorodeoxyglucose positron emission tomography in malignancy of pulmonary artery mimicking pulmonary embolism.
- Authors
Lee, Eun Jeong; Moon, Seung Hwan; Choi, Joon Young; Lee, Kyung Soo; Choi, Yong Soo; Choe, Yearn Seong; Lee, Kyung‐Han; Kim, Byung‐Tae
- Abstract
Background The role of 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (18 F- FDG PET/ CT) in evaluating pulmonary artery lesions has not yet been established. The purpose of this study is to evaluate the usefulness of 18 F- FDG PET/ CT imaging in differentiating malignant from benign pulmonary artery ( PA) lesions. Methods In this retrospective study, 18 subjects with 26 low-attenuated filling defects suspicious for PA malignancy on contrast-enhanced chest CT were enrolled; all of whom subsequently underwent 18 F- FDG PET/ CT. The maximum standardized uptake value ( SUVmax) for all PA lesions, defined as the 18 F- FDG uptake, was measured. The final diagnosis was then determined by pathological findings, follow-up chest CT or clinical follow-up, and compared with the PET imaging. Results In total, 6 PA sarcomas, 5 tumour embolism, and 15 pulmonary thromboembolism ( PTE) occurred in this cohort. Not only was the SUVmax of the malignant PA lesions (10.2 ± 10.8) was significantly higher than that associated with PTE (1.7 ± 0.3; P < 0.001), no overlap occurred between groups. Conversely, no statistically significant difference in SUVmax occurred between PA sarcomas (12.8 ± 14.7) and tumour embolism (7.0 ± 1.32; P = 1.000). Conclusions 18 F- FDG PET/ CT is a useful imaging modality for differentiating malignant from benign PA lesions in patients with inconclusive low-attenuation filling defects on contrast-enhanced chest CT.
- Subjects
PULMONARY artery; PULMONARY embolism; POSITRON emission tomography; CANCER diagnosis; THROMBOEMBOLISM; CANCER
- Publication
ANZ Journal of Surgery, 2013, Vol 83, Issue 5, p342
- ISSN
1445-1433
- Publication type
Article
- DOI
10.1111/j.1445-2197.2012.06205.x