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- Title
Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound.
- Authors
Farr, Ellen; Wolfe, Alexis R.; Deshmukh, Swati; Rydberg, Leslie; Soriano, Rachna; Walter, James M.; Boon, Andrea J.; Wolfe, Lisa F.; Franz, Colin K.
- Abstract
Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end‐expiration) for the post‐COVID‐19 compared to non‐COVID‐19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post‐COVID‐19.
- Subjects
COVID-19; ULTRASONIC imaging; RESPIRATORY muscles; DIAPHRAGM (Anatomy); COVID-19 pandemic
- Publication
Annals of Clinical & Translational Neurology, 2021, Vol 8, Issue 8, p1745
- ISSN
2328-9503
- Publication type
Article
- DOI
10.1002/acn3.51416