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- Title
In vivo evidence of exosome-mediated Aβ neurotoxicity.
- Authors
Elsherbini, Ahmed; Qin, Haiyan; Zhu, Zhihui; Tripathi, Priyanka; Crivelli, Simone M.; Bieberich, Erhard
- Abstract
Keywords: Astrocytes; Exosomes; Mitochondria; Ceramide; Amyloid EN Astrocytes Exosomes Mitochondria Ceramide Amyloid 1 3 3 07/08/20 20200706 NES 200706 Alzheimer's disease (AD) is the most prevalent form of dementia in elderly patients. Representative photomicrographs of (a) WT exosomes and (b) 5xFAD exosomes injected in brains of WT mice showing PLA complex formation (green) inside neurons (blue) in brains injected with 5xFAD exosomes. Astrocytes, Exosomes, Mitochondria, Ceramide, Amyloid.
- Subjects
NEUROTOXICOLOGY; VESICLES (Cytology); EXOSOMES; BLOOD circulation
- Publication
Acta Neuropathologica Communications, 2020, Vol 8, Issue 1, p1
- ISSN
2051-5960
- Publication type
Letter
- DOI
10.1186/s40478-020-00981-y