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- Title
Yüksek Riskli HPV Pozitif Sitolojik Sonuçların, Kolposkopik Biyopsi Sonuçları ile Karşılaştırılması.
- Authors
KARAÇOR, Talip; SAK, Sibel; BARUT, Mert Ulaş; PEKER, Nurullah; SAK, Muhammet Erdal
- Abstract
Background: The aim of the present study was to evaluate the pathologic results of colposcopic examination of patients with High Risk HPV (HR-HPV) who have normal or abnormal cytologic findings and to identify the distribution of HPV types with biopsy results. Materials and Methods: The present study was performed between January 2017 and September 2017 in patients who attended to Harran University Obstetrics and Gynecology Clinic for routine gynecological control or any gynecological complaints. Patients were divided into 3 groups of 20-30, 31-40 and over 40 years old. Pap smear and swab samples were taken concurrently from cervical transformation zone and external cervical ostium and presence of high-risk HPV-DNA were searched. Eighty-four patients with HR-HPV who have normal or abnormal cytologic findings were included in the study. Results: The smear results of 84 patients with HR-HPV positivity were reported as 61. 9% inflammation, 6% ASCUS, 17.9% LSIL, 17.9% HSIL, 1.2% ASC-H and 2.4% atrophy. The most common colposcopic biopsy was CIN I (21.2%) in patients with inflammatory cytological result, CIN II (40%) in patients with ASCUS and epithelial hyperplasia (33.3%) in patients with LSIL. Patients with HSIL cytological result had 44.4% both CIN II and CIN III, 11.1% CIN I pathologic diagnoses. HPV 16 was detected in two patients with squamous cancer and HPV 18 was detected in one patient with squamous cancer. HPV 16 and HPV 18 were detected in two patients who had a cervical adenocarcinoma diagnosis. Conclusion: In HR-HPV positive patients, colposcopic biopsy independent of smear results is likely to detect the presence of dysplasic lesions. With more in the future, we think HR-HPV screening alone may take place of the smear test.
- Subjects
PAPILLOMAVIRUS disease diagnosis; DNA analysis; ACADEMIC medical centers; HYPERPLASIA; ADENOCARCINOMA; BIOPSY; CERVIX uteri diseases; COLPOSCOPY; DYSPLASIA; EPITHELIAL cell tumors; INFLAMMATION; MATERNAL health services; PAP test; PAPILLOMAVIRUS diseases; CERVIX uteri tumors; GYNECOLOGIC care; ATROPHY; CERVICAL intraepithelial neoplasia; DISEASE risk factors
- Publication
Journal of Harran University Medical Faculty / Harran Üniversitesi Tıp Fakültesi Dergisi, 2019, Vol 16, Issue 3, p540
- ISSN
1304-9623
- Publication type
Article
- DOI
10.35440/hutfd.649689