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- Title
Cover Picture: A Rapid, Amplification-Free, and Sensitive Diagnostic Assay for Single-Step Multiplexed Fluorescence Detection of MicroRNA (Angew. Chem. Int. Ed. 34/2015).
- Authors
Jin, Zongwen; Geißler, Daniel; Qiu, Xue; Wegner, K. David; Hildebrandt, Niko
- Abstract
The simple, sensitive, and selective detection of short‐sequence microRNAs is very challenging. In their Communication on page 10024 ff. N. Hildebrandt and co‐workers present a single‐step “mix‐and‐measure” FRET assay for the multiplexed detection of different microRNAs. The careful design of the biophotonic probe and time‐gated FRET from a luminescent Tb complex to three difference fluorescent dyes are crucial to this microRNA test for multiplexed clinical diagnostics.
- Subjects
PEROVSKITE; SOLAR cells; PHOTOCHROMIC materials
- Publication
Angewandte Chemie International Edition, 2015, Vol 54, Issue 34, p9725
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201506281