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- Title
Prognostic factors in hairy cell leukemia (leukemic reticuloendotheliosis).
- Authors
Stewart, David J.; Smith, Terry L.; Keating, Michael J.; McCredie, Kenneth B.; Hersh, Evan M.; Quesada, Jorge; Freireich, Emil J.; Stewart, D J; Smith, T L; Keating, M J; McCredie, K B; Hersh, E M; Quesada, J; Freireich, E J
- Abstract
Prognostic factors were examined in 31 patients with hairy cell leukemia seen at M. D. Anderson Hospital. Long survival from presentation was significantly associated with ease of aspiration of iliac crest bone marrow, absence of major infection, hemoglobin greater than 10 g/dl, and absence of a prior history of pneumonia. Long survival from splenectomy was associated most closely with absence of a prediagnosis history of pneumonia, suggesting that a long-standing host defense abnormality may exist that is not corrected by splenectomy. Generally, patients with sustained improvement in hematologic parameters postsplenectomy lived longest from splenectomy, although the results were not statistically significant.
- Publication
Cancer (0008543X), 1984, Vol 53, Issue 5, p1198
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19840301)53:5<1198::AID-CNCR2820530529>3.0.CO;2-8