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- Title
Congenital Omphalocele and Polyhydramnios: A Study of 52 Cases.
- Authors
Ozawa, Katsusuke; Ishikawa, Hiroshi; Maruyama, Yasuyo; Nagata, Tomoko; Nagase, Hiromi; Itani, Yasufumi; Kurosawa, Kenji; Yamanaka, Michiko
- Abstract
Introduction: Unlike gastroschisis, congenital omphalocele is often associated with other anomalies and is frequently complicated by polyhydramnios. We examined the relationships between polyhydramnios, pregnancy outcome and fetal prognosis.Patients and Methods: Clinical data from cases diagnosed antenatally with congenital omphalocele from 1993 to 2006 were analyzed retrospectively. Results: Fifty-two cases were diagnosed antenatally with congenital omphalocele, and 38 of these pregnancies resulted in delivered infants. Of these 38 pregnancies, 55.3% were preterm births before 37 weeks of gestation. The mean birth weight was 2,148 g (n = 38). Associated anomalies were recognized in 29 cases (76.3%), including 13 cases (34.2%) of chromosomal aberrations. There were 2 cases of trisomy 13, 10 cases of trisomy 18 and 1 case of trisomy 21. Polyhydramnios was detected in 14 cases (36.8%), and other anomalies were present in all of these cases. Discussion: For antenatal evaluation in cases of congenital omphalocele, it is important to examine the fetus for associated anomalies or underlying disease, especially when polyhydramnios is detected. Copyright © 2011 S. Karger AG, Basel
- Subjects
UMBILICAL hernia; GENETIC disorders; HUMAN abnormalities; GENETIC disorders in children; DOWN syndrome; HEALTH outcome assessment; MEDICAL statistics
- Publication
Fetal Diagnosis & Therapy, 2011, Vol 30, Issue 3, p184
- ISSN
1015-3837
- Publication type
Article
- DOI
10.1159/000327542