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Introducing the COST Action 'Improving the Quality of Biomedical Science with 3Rs Concepts' (IMPROVE).
Published in:
Alternatives to Laboratory Animals, 2024, v. 52, n. 6, p. 326, doi. 10.1177/02611929241286024
By:
- Kitsara, Maria;
- Smajlhodžić-Deljo, Merima;
- Gurbeta Pokvic, Lejla;
- Bert, Bettina;
- Bubalo, Nataliia;
- Erden, Sevilay;
- Franco, Nuno Henrique;
- Chirico, Giuseppe;
- Gómez Raja, Jonathan;
- Gonzalez-Uarquin, Fernando;
- Lang, Annemarie;
- Linklater, Nicole;
- Mojsova, Sandra;
- Olsson, I. Anna S.;
- Sandvig, Ioanna;
- Schaffert, Alexandra;
- Schmit, Marthe;
- Schober, Sophie;
- Sevastre, Bogdan;
- Wilflingseder, Doris
Publication type:
Article
A Human Osteochondral Tissue Model Mimicking Cytokine-Induced Key Features of Arthritis In Vitro.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 128, doi. 10.3390/ijms22010128
By:
- Damerau, Alexandra;
- Pfeiffenberger, Moritz;
- Weber, Marie-Christin;
- Burmester, Gerd-Rüdiger;
- Buttgereit, Frank;
- Gaber, Timo;
- Lang, Annemarie
Publication type:
Article
Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 865, doi. 10.3390/ijms21030865
By:
- Gaber, Timo;
- Brinkman, Antonia Clara Katharina;
- Pienczikowski, Justyna;
- Diesing, Karoline;
- Damerau, Alexandra;
- Pfeiffenberger, Moritz;
- Lang, Annemarie;
- Ohrndorf, Sarah;
- Burmester, Gerd-Rüdiger;
- Buttgereit, Frank;
- Hoff, Paula
Publication type:
Article
CTLA-4 Mediates Inhibitory Function of Mesenchymal Stem/Stromal Cells.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 8, p. 2312, doi. 10.3390/ijms19082312
By:
- Gaber, Timo;
- Schönbeck, Kerstin;
- Hoff, Holger;
- Tran, Cam Loan;
- Strehl, Cindy;
- Lang, Annemarie;
- Ohrndorf, Sarah;
- Pfeiffenberger, Moritz;
- Röhner, Eric;
- Matziolis, Georg;
- Burmester, Gerd-R.;
- Buttgereit, Frank;
- Hoff, Paula
Publication type:
Article
A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.
Published in:
International Journal of Molecular Sciences, 2017, v. 18, n. 3, p. 583, doi. 10.3390/ijms18030583
By:
- Hoff, Paula;
- Gaber, Timo;
- Strehl, Cindy;
- Jakstadt, Manuela;
- Hoff, Holger;
- Schmidt-Bleek, Katharina;
- Lang, Annemarie;
- Röhner, Eric;
- Huscher, Dörte;
- Matziolis, Georg;
- Burmester, Gerd-Rüdiger;
- Schmidmaier, Gerhard;
- Perka, Carsten;
- Duda, Georg N.;
- Buttgereit, Frank
Publication type:
Article
A buprenorphine depot formulation provides effective sustained post-surgical analgesia for 72 h in mouse femoral fracture models.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-30641-9
By:
- Wolter, Angelique;
- Bucher, Christian H.;
- Kurmies, Sebastian;
- Schreiner, Viktoria;
- Konietschke, Frank;
- Hohlbaum, Katharina;
- Klopfleisch, Robert;
- Löhning, Max;
- Thöne-Reineke, Christa;
- Buttgereit, Frank;
- Huwyler, Jörg;
- Jirkof, Paulin;
- Rapp, Anna E.;
- Lang, Annemarie
Publication type:
Article
Local immune cell contributions to fracture healing in aged individuals – A novel role for interleukin 22.
Published in:
Experimental & Molecular Medicine EMM, 2022, v. 54, n. 8, p. 1262, doi. 10.1038/s12276-022-00834-9
By:
- Bucher, Christian H.;
- Berkmann, Julia C.;
- Burkhardt, Lisa-Marie;
- Paschke, Carolin;
- Schlundt, Claudia;
- Lang, Annemarie;
- Wolter, Angelique;
- Damerau, Alexandra;
- Geissler, Sven;
- Volk, Hans-Dieter;
- Duda, Georg N.;
- Schmidt-Bleek, Katharina
Publication type:
Article
Spatial Distribution of Macrophages During Callus Formation and Maturation Reveals Close Crosstalk Between Macrophages and Newly Forming Vessels.
Published in:
Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02588
By:
- Stefanowski, Jonathan;
- Lang, Annemarie;
- Rauch, Ariana;
- Aulich, Linus;
- Köhler, Markus;
- Fiedler, Alexander F.;
- Buttgereit, Frank;
- Schmidt-Bleek, Katharina;
- Duda, Georg N.;
- Gaber, Timo;
- Niesner, Raluca A.;
- Hauser, Anja E.
Publication type:
Article
Embracing ethical research: Implementing the 3R principles into fracture healing research for sustainable scientific progress.
Published in:
Journal of Orthopaedic Research, 2024, v. 42, n. 3, p. 568, doi. 10.1002/jor.25741
By:
- Anup, Amritha;
- Dieterich, Sandra;
- Oreffo, Richard O. C.;
- Dailey, Hannah L.;
- Lang, Annemarie;
- Haffner‐Luntzer, Melanie;
- Hixon, Katherine R.
Publication type:
Article
The In Vitro Human Fracture Hematoma Model - A Tool for Preclinical Drug Testing.
Published in:
Altex, 2020, v. 37, n. 4, p. 561, doi. 10.14573/altex.1910211
By:
- Pfeiffenberger, Moritz;
- Hoff, Paula;
- Thöne-Reineke, Christa;
- Buttgereit, Frank;
- Lang, Annemarie;
- Gaber, Timo
Publication type:
Article
In silico Methods - Computational Alternatives to Animal Testing.
Published in:
Altex, 2018, v. 35, n. 1, p. 126, doi. 10.14573/altex.1712031
By:
- Lang, Annemarie;
- Volkamer, Andrea;
- Behm, Laura;
- Röblitz, Susanna;
- Ehrig, Rainald;
- Schneider, Marlon;
- Geris, Liesbet;
- Wichard, Joerg;
- Buttgereit, Frank
Publication type:
Article
Optimization of a nonviral transfection system to evaluate Cox-2 controlled interleukin-4 expression for osteoarthritis gene therapy in vitro.
Published in:
Journal of Gene Medicine, 2014, v. 16, n. 11/12, p. 352, doi. 10.1002/jgm.2812
By:
- Lang, Annemarie;
- Neuhaus, Johannes;
- Pfeiffenberger, Moritz;
- Schröder, Erik;
- Ponomarev, Igor;
- Weber, Yvonne;
- Gaber, Timo;
- Schmidt, Michael F. G.
Publication type:
Article
Scaffold Guided Bone Regeneration for the Treatment of Large Segmental Defects in Long Bones.
Published in:
Biomedicines, 2023, v. 11, n. 2, p. 325, doi. 10.3390/biomedicines11020325
By:
- Schulze, Frank;
- Lang, Annemarie;
- Schoon, Janosch;
- Wassilew, Georgi I.;
- Reichert, Johannes
Publication type:
Article
Fracture Healing Research—Shift towards In Vitro Modeling?
Published in:
Biomedicines, 2021, v. 9, n. 7, p. 748, doi. 10.3390/biomedicines9070748
By:
- Pfeiffenberger, Moritz;
- Damerau, Alexandra;
- Lang, Annemarie;
- Buttgereit, Frank;
- Hoff, Paula;
- Gaber, Timo
Publication type:
Article
The Rise of Three Rs Centres and Platforms in Europe*.
Published in:
Alternatives to Laboratory Animals, 2022, v. 50, n. 2, p. 90, doi. 10.1177/02611929221099165
By:
- Neuhaus, Winfried;
- Reininger-Gutmann, Birgit;
- Rinner, Beate;
- Plasenzotti, Roberto;
- Wilflingseder, Doris;
- De Kock, Joery;
- Vanhaecke, Tamara;
- Rogiers, Vera;
- Jírová, Dagmar;
- Kejlová, Kristina;
- Knudsen, Lisbeth E.;
- Nielsen, Rasmus Normann;
- Kleuser, Burkhard;
- Kral, Vivian;
- Thöne-Reineke, Christa;
- Hartung, Thomas;
- Pallocca, Giorgia;
- Leist, Marcel;
- Hippenstiel, Stefan;
- Lang, Annemarie
Publication type:
Article
Animal Models of Osteoarthritis Part 1–Preclinical Small Animal Models: Challenges and Opportunities for Drug Development.
Published in:
Current Protocols, 2022, v. 2, n. 11, p. 1, doi. 10.1002/cpz1.596
By:
- Rios, Jaqueline Lourdes;
- Sapède, Dora;
- Djouad, Farida;
- Rapp, Anna E.;
- Lang, Annemarie;
- Larkin, Jonathan;
- Ladel, Christoph;
- Mobasheri, Ali
Publication type:
Article
Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-05915-1
By:
- Lang, Annemarie;
- Benn, Andreas;
- Collins, Joseph M.;
- Wolter, Angelique;
- Balcaen, Tim;
- Kerckhofs, Greet;
- Zwijsen, An;
- Boerckel, Joel D.
Publication type:
Article
Journey into Bone Models: A Review.
Published in:
Genes, 2018, v. 9, n. 5, p. 247, doi. 10.3390/genes9050247
By:
- Scheinpflug, Julia;
- Pfeiffenberger, Moritz;
- Damerau, Alexandra;
- Schwarz, Franziska;
- Textor, Martin;
- Lang, Annemarie;
- Schulze, Frank
Publication type:
Article
Hypoxia and mesenchymal stromal cells as key drivers of initial fracture healing in an equine in vitro fracture hematoma model.
Published in:
PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0214276
By:
- Pfeiffenberger, Moritz;
- Bartsch, Janika;
- Hoff, Paula;
- Ponomarev, Igor;
- Barnewitz, Dirk;
- Thöne-Reineke, Christa;
- Buttgereit, Frank;
- Gaber, Timo;
- Lang, Annemarie
Publication type:
Article
Functional Scaffold‐Free Bone Equivalents Induce Osteogenic and Angiogenic Processes in a Human In Vitro Fracture Hematoma Model.
Published in:
Journal of Bone & Mineral Research, 2021, v. 36, n. 6, p. 1189, doi. 10.1002/jbmr.4267
By:
- Pfeiffenberger, Moritz;
- Damerau, Alexandra;
- Ponomarev, Igor;
- Bucher, Christian H;
- Chen, Yuling;
- Barnewitz, Dirk;
- Thöne‐Reineke, Christa;
- Hoff, Paula;
- Buttgereit, Frank;
- Gaber, Timo;
- Lang, Annemarie
Publication type:
Article
Evaluating rearing behaviour as a model-specific pain indicator in mouse osteotomy models.
Published in:
Laboratory Animals, 2024, v. 58, n. 1, p. 9, doi. 10.1177/00236772231183197
By:
- Wolter, Angelique;
- Jirkof, Paulin;
- Thöne-Reineke, Christa;
- Rapp, Anna E;
- Lang, Annemarie
Publication type:
Article
How to publish a case report in Laboratory Animals ?
Published in:
Laboratory Animals, 2023, v. 57, n. 1, p. 2, doi. 10.1177/00236772221103964
By:
- Sánchez-Morgado, José M.;
- Whitfield, Lucy;
- Tremoleda, Jordi L;
- Mocho, Jean-Philippe;
- Lang, Annemarie;
- Jirkof, Paulin
Publication type:
Article
Is it time for a 'Culture of Carers'?
Published in:
Laboratory Animals, 2022, v. 56, n. 6, p. 498, doi. 10.1177/00236772221102078
By:
- Sánchez-Morgado, José M.;
- Jirkof, Paulin;
- Lang, Annemarie;
- Mocho, Jean-Philippe;
- Tremoleda, Jordi L
Publication type:
Article
Report from the 11th edition of the World Congress on Alternatives and Animal Use in the Life Sciences (WC11).
Published in:
Laboratory Animals, 2022, v. 56, n. 1, p. 101, doi. 10.1177/00236772211064174
By:
- Lang, Annemarie;
- Jirkof, Paulin;
- Mocho, J-P;
- Sanchez-Morgado, José;
- Tremoleda, Jordi L.
Publication type:
Article
Do you want to join our Editorial Board?
Published in:
2021
By:
- Jirkof, Paulin;
- Lang, Annemarie;
- Mocho, J-P;
- Sanchez-Morgado, José;
- Tremoleda, Jordi L.
Publication type:
Editorial
Osteotomy models – the current status on pain scoring and management in small rodents.
Published in:
Laboratory Animals, 2016, v. 50, n. 6, p. 433, doi. 10.1177/0023677216675007
By:
- Lang, Annemarie;
- Schulz, Anja;
- Ellinghaus, Agnes;
- Schmidt-Bleek, Katharina
Publication type:
Article

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