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CD34-negative hematopoietic stem cells show distinct expression profiles of homing molecules that limit engraftment in mice and sheep.
Published in:
2017
By:
- Abe, Tomoyuki;
- Matsuoka, Yoshikazu;
- Nagao, Yoshikazu;
- Sonoda, Yoshiaki;
- Hanazono, Yutaka
Publication type:
journal article
Selective expansion of transduced cells for hematopoietic stem cell gene therapy.
Published in:
2002
By:
- Kume, Akihiro;
- Hanazono, Yutaka;
- Mizukami, Hiroaki;
- Okada, Takashi;
- Ozawa, Keiya
Publication type:
journal article
Improved Safety of Hematopoietic Transplantation with Monkey Embryonic Stem Cells in the Allogeneic Setting.
Published in:
Stem Cells, 2006, v. 24, n. 6, p. 1450, doi. 10.1634/stemcells.2005-0391
By:
- Shibata, Hiroaki;
- Ageyama, Naohide;
- Tanaka, Yujiro;
- Kishi, Yukiko;
- Sasaki, Kyoko;
- Nakamura, Shinichiro;
- Muramatsu, Shin-ichi;
- Hayashi, Satoshi;
- Kitano, Yoshihiro;
- Terao, Keiji;
- Hanazono, Yutaka
Publication type:
Article
Germ-free pigs and their applications.
Published in:
Experimental Animals, 2021, v. 70, p. 66
By:
- Hiromasa Hara;
- Yutaka Hanazono
Publication type:
Article
DNA methylation profiles provide a viable index for porcine pluripotent stem cells.
Published in:
Genesis: The Journal of Genetics & Development, 2013, v. 51, n. 11, p. 763, doi. 10.1002/dvg.22423
By:
- Arai, Yoshikazu;
- Ohgane, Jun;
- Fujishiro, Shuh‐hei;
- Nakano, Kazuaki;
- Matsunari, Hitomi;
- Watanabe, Masahito;
- Umeyama, Kazuhiro;
- Azuma, Dai;
- Uchida, Naomi;
- Sakamoto, Nozomu;
- Makino, Tomohiro;
- Yagi, Shintaro;
- Shiota, Kunio;
- Hanazono, Yutaka;
- Nagashima, Hiroshi
Publication type:
Article
Collection and analysis of hematopoietic progenitor cells from cynomolgus macaques (Macaca fascicularis): Assessment of cross-reacting monoclonal antibodies.
Published in:
American Journal of Primatology, 2003, v. 61, n. 1, p. 3, doi. 10.1002/ajp.10104
By:
- Hiroaki Shibata;
- Yutaka Hanazono;
- Naohide Ageyama;
- Takeyuki Nagashima;
- Yasuji Ueda;
- Mamoru Hasegawa;
- Keiya Ozawa;
- Yasuhiro Yoshikawa;
- Keiji Terao
Publication type:
Article
THE SIGNAL TRANSDUCTION THROUGH GRB2/ASH IN HEMATOPOIETIC CELLS.
Published in:
Leukemia (08876924), 1997, v. 11, p. 405
By:
- ODAI, Hideharu;
- HANAZONO, Yutaka;
- SASAKI, Kou;
- IWAMATU, Akihiro;
- YAZAKI, Yoshio;
- HIRAI, Hisamaru
Publication type:
Article
Secretory GFP reconstitution labeling of neighboring cells interrogates cell–cell interactions in metastatic niches.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43855-2
By:
- Minegishi, Misa;
- Kuchimaru, Takahiro;
- Nishikawa, Kaori;
- Isagawa, Takayuki;
- Iwano, Satoshi;
- Iida, Kei;
- Hara, Hiromasa;
- Miura, Shizuka;
- Sato, Marika;
- Watanabe, Shigeaki;
- Shiomi, Akifumi;
- Mabuchi, Yo;
- Hamana, Hiroshi;
- Kishi, Hiroyuki;
- Sato, Tatsuyuki;
- Sawaki, Daigo;
- Sato, Shigeru;
- Hanazono, Yutaka;
- Suzuki, Atsushi;
- Kohro, Takahide
Publication type:
Article
MHC-Matched Induced Pluripotent Stem Cells Can Attenuate Cellular and Humoral Immune Responses but Are Still Susceptible to Innate Immunity in Pigs.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098319
By:
- Mizukami, Yoshihisa;
- Abe, Tomoyuki;
- Shibata, Hiroaki;
- Makimura, Yukitoshi;
- Fujishiro, Shuh-hei;
- Yanase, Kimihide;
- Hishikawa, Shuji;
- Kobayashi, Eiji;
- Hanazono, Yutaka
Publication type:
Article
Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076478
By:
- Watanabe, Masahito;
- Nakano, Kazuaki;
- Matsunari, Hitomi;
- Matsuda, Taisuke;
- Maehara, Miki;
- Kanai, Takahiro;
- Kobayashi, Mirina;
- Matsumura, Yukina;
- Sakai, Rieko;
- Kuramoto, Momoko;
- Hayashida, Gota;
- Asano, Yoshinori;
- Takayanagi, Shuko;
- Arai, Yoshikazu;
- Umeyama, Kazuhiro;
- Nagaya, Masaki;
- Hanazono, Yutaka;
- Nagashima, Hiroshi
Publication type:
Article
Generating Porcine Chimeras Using Inner Cell Mass Cells and Parthenogenetic Preimplantation Embryos.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061900
By:
- Nakano, Kazuaki;
- Watanabe, Masahito;
- Matsunari, Hitomi;
- Matsuda, Taisuke;
- Honda, Kasumi;
- Maehara, Miki;
- Kanai, Takahiro;
- Hayashida, Gota;
- Kobayashi, Mirina;
- Kuramoto, Momoko;
- Arai, Yoshikazu;
- Umeyama, Kazuhiro;
- Fujishiro, Shuh-hei;
- Mizukami, Yoshihisa;
- Nagaya, Masaki;
- Hanazono, Yutaka;
- Nagashima, Hiroshi
Publication type:
Article
Reduction of CTLL-2 cytotoxicity by induction of apoptosis with a Fas-estrogen receptor chimera.
Published in:
Cancer Science, 2003, v. 94, n. 7, p. 639, doi. 10.1111/j.1349-7006.2003.tb01496.x
By:
- Kametaka, Minako;
- Kume, Akihiro;
- Okada, Takashi;
- Mizukami, Hiroaki;
- Hanazono, Yutaka;
- Ozawa, Keiya
Publication type:
Article
c-Cbl Is Inducibly Tyrosine-phosphorylated by Epidermal Growth Factor Stimulation in Fibroblasts, and Constitutively Tyrosine-phosphorylated and Associated with v-Src in v- src-transformed Fibroblasts.
Published in:
Cancer Science, 1995, v. 86, n. 12, p. 1119, doi. 10.1111/j.1349-7006.1995.tb03303.x
By:
- Odai, Hideharu;
- Sasaki, Ko;
- Hanazono, Yutaka;
- Ueno, Hiroo;
- Tanaka, Tomoyuki;
- Miyagawa, Kiyoshi;
- Mitani, Kinuko;
- Yazaki, Yoshio;
- Hirai, Hisamaru
Publication type:
Article
Tyrosine Phosphorylation of the Proto-oncogene Product Vav and Its Association with the Adapter Grb2/Ash in a Human Leukemia Cell Line UT-7.
Published in:
Cancer Science, 1995, v. 86, n. 4, p. 336, doi. 10.1111/j.1349-7006.1995.tb03061.x
By:
- Hanazono, Yutaka;
- Sasaki, Ko;
- Odai, Hideharu;
- Mimura, Toshihide;
- Mitani, Kinuko;
- Yazaki, Yoshio;
- Hirai, Hisamaru
Publication type:
Article
Distribution of Human Granulocyte Colony-stimulating Factor Receptors on Hematopoietic and Nonhematopoietic Tumor Cell Lines.
Published in:
Cancer Science, 1990, v. 81, n. 6/7, p. 560, doi. 10.1111/j.1349-7006.1990.tb02608.x
By:
- Kuwaki, Tomoaki;
- Hosoi, Takayuki;
- Hanazono, Yutaka;
- Tsumura, Haruhiko;
- Ishikawa, Fuyuki;
- Miyazono, Kohei;
- Miyagawa, Kiyoshi;
- Takaku, Fumimaro
Publication type:
Article
Non-Invasive In Vivo Bioimaging in Pigs.
Published in:
International Journal of Translational Medicine, 2024, v. 4, n. 3, p. 570, doi. 10.3390/ijtm4030039
By:
- Abe, Tomoyuki;
- Endo, Kazuhiro;
- Hanazono, Yutaka;
- Kobayashi, Eiji
Publication type:
Article
Ultra-Deep Bisulfite Sequencing to Detect Specific DNA Methylation Patterns of Minor Cell Types in Heterogeneous Cell Populations: An Example of the Pituitary Tissue.
Published in:
PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146498
By:
- Arai, Yoshikazu;
- Fukukawa, Hisho;
- Atozi, Takanori;
- Matsumoto, Shoma;
- Hanazono, Yutaka;
- Nagashima, Hiroshi;
- Ohgane, Jun
Publication type:
Article
In vivo expansion of gene-modified hematopoietic cells by a novel selective amplifier gene utilizing the erythropoietin receptor as a molecular switch.
Published in:
Journal of Gene Medicine, 2004, v. 6, n. 1, p. 22, doi. 10.1002/jgm.467
By:
- Nagashima, Takeyuki;
- Ueda, Yasuji;
- Hanazono, Yutaka;
- Kume, Akihiro;
- Shibata, Hiroaki;
- Ageyama, Naohide;
- Terao, Keiji;
- Ozawa, Keiya;
- Hasegawa, Mamoru
Publication type:
Article
Efficient gene transfer of a simian immuno-deficiency viral vector into cardiomyocytes derived from primate embryonic stem cells.
Published in:
Journal of Gene Medicine, 2003, v. 5, n. 11, p. 921, doi. 10.1002/jgm.431
By:
- Mihoko Nagata;
- Masafumi Takahashi;
- Shin-ichi Muramatsu;
- Yasuji Ueda;
- Yutaka Hanazono;
- Koichi Takeuchi;
- Koji Okada;
- Yutaka Suzuki;
- Yasushi Kondo;
- Masafumi Suemori;
- Uichi Ikeda;
- Imaharu Nakano;
- Eiji Kobayashi;
- Mamoru Hasegawa;
- Keiya Ozawa;
- Norio Nakatsuji;
- Kazuyuki Shimada
Publication type:
Article
A soluble CAR-SCF fusion protein improves adenoviral vector-mediated gene transferto c-Kit-positive hematopoietic cells.
Published in:
Journal of Gene Medicine, 2003, v. 5, n. 11, p. 929, doi. 10.1002/jgm.430
By:
- Akira Itoh;
- Takashi Okada;
- Hiroyuki Mizuguchi;
- Takao Hayakawa;
- Hiroaki Mizukami;
- Akihiro Kume;
- Masaaki Takatoku;
- Norio Komatsu;
- Yutaka Hanazono
Publication type:
Article
In vivo expansion of transduced murine hematopoietic cells with a selective amplifier gene.
Published in:
Journal of Gene Medicine, 2003, v. 5, n. 3, p. 175, doi. 10.1002/jgm.337
By:
- Kume, Akihiro;
- Koremoto, Masahide;
- Xu, Ruifang;
- Okada, Takashi;
- Mizukami, Hiroaki;
- Hanazono, Yutaka;
- Hasegawa, Mamoru;
- Ozawa, Keiya
Publication type:
Article
Introduction of the green fluorescent protein gene into hematopoietic stem cells results in prolonged discrepancy of in vivo transduction levels between bone marrow progenitors and peripheral blood cells in nonhuman primates.
Published in:
Journal of Gene Medicine, 2002, v. 4, n. 5, p. 470, doi. 10.1002/jgm.307
By:
- Hanazono, Yutaka;
- Terao, Keiji;
- Shibata, Hiroaki;
- Nagashima, Takeyuki;
- Ageyama, Naohide;
- Asano, Takayuki;
- Ueda, Yasuji;
- Kato, Ikunoshin;
- Kume, Akihiro;
- Hasegawa, Mamoru;
- Ozawa, Keiya
Publication type:
Article
High-Level in Vivo Gene Marking after Gene-Modified Autologous Hematopoietic Stem Cell Transplantation without Marrow Conditioning in Nonhuman Primates
Published in:
Molecular Therapy, 2004, v. 10, n. 3, p. 469, doi. 10.1016/j.ymthe.2004.06.146
By:
- Ueda, Kyoji;
- Hanazono, Yutaka;
- Shibata, Hiroaki;
- Ageyama, Naohide;
- Ueda, Yasuji;
- Ogata, Satoko;
- Tabata, Toshiaki;
- Nagashima, Takeyuki;
- Takatoku, Masaaki;
- Kume, Akihiko;
- Ikehara, Susumu;
- Taniwaki, Masafumi;
- Terao, Keiji;
- Hasegawa, Mamoru;
- Ozawa, Keiya
Publication type:
Article
Persistent phenotypic correction of central diabetes insipidus using adeno-associated virus vector expressing Arginine–Vasopressin in brattleboro rats
Published in:
Molecular Therapy, 2003, v. 8, n. 6, p. 895, doi. 10.1016/j.ymthe.2003.08.019
By:
- Ideno, Junichi;
- Mizukami, Hiroaki;
- Honda, Kazufumi;
- Okada, Takashi;
- Hanazono, Yutaka;
- Kume, Akihiro;
- Saito, Toshikazu;
- Ishibashi, Shun;
- Ozawa, Keiya
Publication type:
Article
Highly Efficient Gene Transfer into Primate Embryonic Stem Cells with a Simian Lentivirus Vector
Published in:
Molecular Therapy, 2002, v. 6, n. 2, p. 162, doi. 10.1006/mthe.2002.0655
By:
- Asano, Takayuki;
- Hanazono, Yutaka;
- Ueda, Yasuji;
- Muramatsu, Shin-ichi;
- Kume, Akihiro;
- Suemori, Hirofumi;
- Suzuki, Yutaka;
- Kondo, Yasushi;
- Harii, Kiyonori;
- Hasegawa, Mamoru;
- Nakatsuji, Norio;
- Ozawa, Keiya
Publication type:
Article
Proto-Oncogene Products Vav and c-Cbl Are Involved in the Signal Transduction through Grb2/Ash in Hematopoietic Cells.
Published in:
Acta Haematologica, 1996, v. 95, n. 3/4, p. 236, doi. 10.1159/000203884
By:
- Hanazono, Yutaka;
- Odai, Hideharu;
- Ko Sasaki, K.;
- Iwamatsu, Akihiro;
- Yazaki, Yoshio;
- Hirai, Hisamaru
Publication type:
Article
In Vivo Luciferin–Luciferase Reaction in Micro-Mini Pigs Using Xenogeneic Rat Bone Marrow Transplantation.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8609, doi. 10.3390/ijms25168609
By:
- Abe, Tomoyuki;
- Endo, Kazuhiro;
- Hanazono, Yutaka;
- Kobayashi, Eiji
Publication type:
Article
Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model.
Published in:
Cancer Science, 2009, v. 100, n. 12, p. 2444, doi. 10.1111/j.1349-7006.2009.01328.x
By:
- Masuda, Shigeo;
- Kumano, Keiki;
- Suzuki, Takahiro;
- Tomita, Taisuke;
- Iwatsubo, Takeshi;
- Natsugari, Hideaki;
- Tojo, Arinobu;
- Shibutani, Makoto;
- Mitsumori, Kunitoshi;
- Hanazono, Yutaka;
- Ogawa, Seishi;
- Kurokawa, Mineo;
- Chiba, Shigeru
Publication type:
Article

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