We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Cerebral perfusion information obtained by dynamic contrast-enhanced phase-shift magnetic resonance imaging: comparison with model-free arterial spin labelling.
- Authors
Wirestam, Ronnie; Lindgren, Emelie; van Westen, Danielle; Bloch, Karin Markenroth; Ståhlberg, Freddy; Knutsson, Linda
- Abstract
Phase-shift time curves following a bolus injection of gadolinium contrast agent were registered for grey-matter regions and large vessels in 14 subjects. Deconvolving a tissue phase-shift curve with a phase-based arterial input function resulted in a tissue residue function R(t). The peak value of R(t) provided a relative cerebral blood flow (CBF) index, while the area-to-height ratio of R(t) provided quantitative mean transit time (MTT). For comparison, quantitative CBF values in grey matter were acquired using model-free arterial spin labelling (ASL). The phase-based relative CBF estimates showed good linear correlation with ASL-based CBF ( r = 0·82). Grey-matter MTT was 4·9 ± 1·1 s (mean ± SD).
- Subjects
PHASE shifters; GADOLINIUM; ARTERIES; MAGNETIC resonance imaging; ELECTRONIC equipment
- Publication
Clinical Physiology & Functional Imaging, 2010, Vol 30, Issue 5, p375
- ISSN
1475-0961
- Publication type
Article
- DOI
10.1111/j.1475-097X.2010.00947.x