We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Roles of TGF‑β signalling pathway‑related lncRNAs in cancer (Review).
- Authors
Hu, Zhizhong; Liu, Yitong; Liu, Meiqi; Zhang, Yang; Wang, Chengkun
- Abstract
Long non-coding RNAs (lncRNAs) are a class of RNAs that are >200 nucleotides in length that do not have the ability to be translated into protein but are associated with numerous diseases, including cancer. The involvement of lncRNAs in the signalling of certain signalling pathways can promote tumour progression; these pathways include the transforming growth factor (TGF)-β signalling pathway, which is related to tumour development. The expression of lncRNAs in various tumour tissues is specific, and their interaction with the TGF-β signalling pathway indicates that they may serve as new tumour markers and therapeutic targets. The present review summarized the role of TGF-β pathway-associated lncRNAs in regulating tumorigenesis in different types of cancer and their effects on the TGF-β signalling pathway.
- Subjects
LINCRNA; TRANSFORMING growth factors; CELLULAR signal transduction; TUMOR markers; NUCLEOTIDES
- Publication
Oncology Letters, 2023, Vol 25, Issue 3, pN.PAG
- ISSN
1792-1074
- Publication type
Article
- DOI
10.3892/ol.2023.13693