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- Title
Hyperglucagonaemia and necrolytic migratory erythema in cirrhosis -- possible pseudoglucagonoma syndrome.
- Authors
Doyle, John A.; Schroeter, Arnold L.; Rogers III, Roy S.
- Abstract
Necrolytic migratory erythema is the distinctive cutaneous eruption seen with glucagon-producing tumours of the pancreas. Recognition of this eruption is important because it may lead to the early diagnosis of a glucagonoma. Recently, we saw a patient who had necrolytic migratory erythema, hyper-glucagonaemia, and cirrhosis of the liver with no evidence of pancreatic tumour while alive or at autopsy. Serum glucagon levels during the period of observation and during an oral glucose tolerance test suggested that the hyperglucagonaemia was not due to an occult glucagon-producing tumour but may have been the result of advanced hepatic cirrhosis.
- Subjects
ERYTHEMA; CUTANEOUS manifestations of general diseases; GLUCAGON; CIRRHOSIS of the liver; GLUCOSE; SERUM
- Publication
British Journal of Dermatology, 1979, Vol 101, Issue 5, p581
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1979.tb11890.x