We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Recurrent venous and arterial thrombosis during anticoagulant treatment in a patient with immune thrombocytopenic purpura exacerbation.
- Authors
Poparlan, Georgiana; Mihalcia, Mirela Mihaela; Mitu, Ovidiu; Tarniceriu, Cristina; Statescu, Cristian; Onofrei, Viviana; Namat, Razan Al; Buburuz, Ana Maria; Costache, Irina Iuliana; Petris, Antoniu Octavian
- Abstract
Treatment of patients with immune thrombocytopenic purpura (ITP) associated with recurrent venous and arterial thrombosis can represent a major challenge. We present the rare case of a 56-year-old female who was first diagnosed with severe ITP at the age of 36. She required corticosteroid therapy and splenectomy in evolution. However, in the last three years she had several episodes of recurrent venous thromboembolism for which she required different anticoagulant therapies despite severe thrombocythemia. The patient also developed acute myocardial infarction treated by primary percutaneous coronary intervention that was complicated with acute intrastent thrombosis. Thus, maximal antiplatelet therapy was mandatory. For ITP, the patient received intravenous steroids, platelet transfusion as well as eltrombopag. Moreover, the patient also suffered from a haemorrhagic uterine fibroma that required surgery. Thus, a close multidisciplinary approach was needed for the successful treatment of this patient.
- Subjects
IDIOPATHIC thrombocytopenic purpura; VENOUS thrombosis; ANTIPHOSPHOLIPID syndrome; ANTICOAGULANTS; PERCUTANEOUS coronary intervention; BLOOD platelet transfusion
- Publication
Romanian Journal of Cardiology, 2020, Vol 30, Issue 2, p257
- ISSN
1220-658X
- Publication type
Article