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- Title
Case report: a 10-year-old girl with primary hypoparathyroidism and systemic lupus erythematosus.
- Authors
Borysewicz-Sańczyk, Hanna; Sawicka, Beata; Michalak, Justyna; Wójtowicz, Jerzy; Dobreńko, Elżbieta; Konstantynowicz, Jerzy; Kemp, E. Helen; Thakker, Rajesh V.; Allgrove, Jeremy; Hannan, Fadil M.; Bossowski, Artur
- Abstract
Objectives: Hypoparathyroidism is a rare disease in children that occurs as a result of autoimmune destruction of the parathyroid glands, a defect in parathyroid gland development or secondary to physical parathyroid gland disturbance. Typical symptoms of hypoparathyroidism present as hypocalcaemia and hyperphosphatemia due to decreased parathyroid hormone secretion and may lead to nerve and muscles disturbances resulting in clinical manifestation of tetany, arrhythmias and epilepsy. Currently, there is no conventional hormone replacement treatment for hypoparathyroidism and therapeutic approaches include normalising mineral levels using an oral calcium supplement and active forms of vitamin D. Case presentation: We present the case of a 10-year-old girl with primary hypoparathyroidism who had no prior history of autoimmune disorders, but who subsequently developed systemic lupus erythematosus.
- Publication
Journal of Pediatric Endocrinology & Metabolism, 2020, Vol 33, Issue 9, p1231
- ISSN
0334-018X
- Publication type
Article
- DOI
10.1515/jpem-2020-0015