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- Title
Randomised double-blind, placebocontrolled trial of iron supplementation attenuates fatigue and declining iron stores for female officers-in-training.
- Authors
Booth, Christine K.; Carins, Julia E.; Robertson, Iain K.
- Abstract
Background: Physical training by female military trainees can put them at risk of iron deficiency and inferior health and performance. Purpose: To determine the effect of iron supplementation on iron status, fitness, fatigue, and leisure activities. Material and Methods: In this randomised, double-blind, placebo-controlled trial, female officers-in-training were randomly allocated to treatment (n = 25, 18 mg iron) or placebo tablets (n = 24). Outcomes were iron status, fitness, fatigue, and leisure activity at baseline, seven weeks and 13 weeks. Results: Ferritin declined by midpoint in the placebo group (P = 0.001). There was a treatment effect in the second half of the trial in emotional fatigue (-4.2 to -0.6 95% CI, P = 0.04). There was a negative relationship with iron intake for emotional fatigue (OR 0.61; 0.44 to 0.87 95% CI; P = 0.006) and positive for vigour (OR 1.51; 1.08 to 2.11 95%CI; P = 0.016) and small negative association between initial dietary iron intake and initial serum ferritin (0.2 to 9.2 μg/L 95% CI; P = 0.042). Conclusion: Officer training affects iron status and iron supplementation improves indicators of iron status and emotional fatigue in female officers-in-training.
- Subjects
AUSTRALIA; FATIGUE prevention; FATIGUE (Physiology); IRON deficiency anemia prevention; PHYSICAL fitness; CONFIDENCE intervals; DIET; DIETARY supplements; ALCOHOL drinking; ENZYME-linked immunosorbent assay; FERRITIN; HELICOBACTER diseases; HEMOGLOBINS; IMMUNOGLOBULINS; INGESTION; IRON; MATHEMATICAL statistics; NUTRITION; PLACEBOS; SMOKING; MILITARY personnel; LOGISTIC regression analysis; DATA analysis; PARAMETERS (Statistics); BODY mass index; RANDOMIZED controlled trials; PHYSICAL activity; DESCRIPTIVE statistics; PSYCHOLOGY
- Publication
Journal of Military & Veterans' Health, 2014, Vol 22, Issue 3, p13
- ISSN
1835-1271
- Publication type
Article