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Ligand‐Enabled β‐Methylene C(sp<sup>3</sup>)−H Arylation of Masked Aliphatic Alcohols.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 20, p. 7857, doi. 10.1002/ange.202000632
- By:
- Publication type:
- Article
Mapping the landscape of genetic dependencies in chordoma.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37593-8
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- Publication type:
- Article
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints.
- Published in:
- EMBO Journal, 1998, v. 17, n. 1, p. 159, doi. 10.1093/emboj/17.1.159
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- Publication type:
- Article
Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70.
- Published in:
- EMBO Journal, 1997, v. 16, n. 18, p. 5618, doi. 10.1093/emboj/16.18.5618
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- Publication type:
- Article
An FKBP-Rapamycin-Sensitive, Cyclin-Dependent Kinase Activity that Correlates with the FKBP-Rapamycin-Induced G1 Arrest Point in MG-63 Cells<sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1993, v. 696, n. 1, p. 54, doi. 10.1111/j.1749-6632.1993.tb17142.x
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- Publication type:
- Article
Chemical Perturbation of an Intrinsically Disordered Region of TFIID Distinguishes Two Modes of Transcription Initiation.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.07777
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- Publication type:
- Article
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.05920
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- Publication type:
- Article
ChemBank: a small-molecule screening and cheminformatics resource database.
- Published in:
- Nucleic Acids Research, 2008, v. 36, p. D351
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- Publication type:
- Article
Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28108-y
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- Publication type:
- Article
Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 9, p. 1, doi. 10.1371/journal.pntd.0004094
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- Publication type:
- Article
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines.
- Published in:
- Nature Biotechnology, 2016, v. 34, n. 4, p. 419, doi. 10.1038/nbt.3460
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- Publication type:
- Article
Chemoproteomics quantifies complexity.
- Published in:
- Nature Biotechnology, 2011, v. 29, n. 3, p. 235, doi. 10.1038/nbt.1804
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- Publication type:
- Article
Towards patient-based cancer therapeutics.
- Published in:
- 2010
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- Publication type:
- Opinion
Corrigendum: Large-scale chemical dissection of mitochondrial function.
- Published in:
- 2008
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- Publication type:
- Correction Notice
Large-scale chemical dissection of mitochondrial function.
- Published in:
- Nature Biotechnology, 2008, v. 26, n. 3, p. 343, doi. 10.1038/nbt1387
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- Publication type:
- Article
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.
- Published in:
- Nature Biotechnology, 2004, v. 22, n. 5, p. 595, doi. 10.1038/nbt963
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- Publication type:
- Article
Genetic basis of individual differences in the response to small-molecule drugs in yeast.
- Published in:
- Nature Genetics, 2007, v. 39, n. 4, p. 496, doi. 10.1038/ng1991
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- Publication type:
- Article
The transcriptional profile of Saccharomyces cerevisiae exposed to rapamycin mimics the profile induced by amino acid starvation.
- Published in:
- 1999
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- Publication type:
- Abstract
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres.
- Published in:
- Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1218, doi. 10.1038/nsmb.1897
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- Publication type:
- Article
Catalytic Diastereoselective Petasis Reactions.
- Published in:
- Angewandte Chemie, 2011, v. 123, n. 35, p. 8322, doi. 10.1002/ange.201103271
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- Publication type:
- Article
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay.
- Published in:
- GigaScience, 2017, v. 6, n. 12, p. 1, doi. 10.1093/gigascience/giw014
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- Publication type:
- Article
Quantitative-Proteomic Comparison of Alpha and Beta Cells to Uncover Novel Targets for Lineage Reprogramming.
- Published in:
- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095194
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- Publication type:
- Article
Multiplex Cytological Profiling Assay to Measure Diverse Cellular States.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0080999
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- Publication type:
- Article
GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity.
- Published in:
- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0028808
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- Publication type:
- Article
Empirical Bayes Analysis of Quantitative Proteomics Experiments.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007454
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- Publication type:
- Article
Using Expression and Genotype to Predict Drug Response in Yeast.
- Published in:
- PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0006907
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- Publication type:
- Article
Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors.
- Published in:
- Journal of Infectious Diseases, 2015, v. 211, n. 7, p. 1097, doi. 10.1093/infdis/jiu565
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- Publication type:
- Article
Ceestatin, a Novel Small Molecule Inhibitor of Hepatitis C Virus Replication, Inhibits 3-Hydroxy-3-Methylglutaryl-Coenzyme A Synthase.
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides.
- Published in:
- Biomolecules (2218-273X), 2020, v. 10, n. 1, p. 1, doi. 10.3390/biom10010001
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- Publication type:
- Article
Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer.
- Published in:
- Oncogene, 2005, v. 24, n. 28, p. 4531, doi. 10.1038/sj.onc.1208646
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- Publication type:
- Article
Metabolomic adaptations and correlates of survival to immune checkpoint blockade.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12361-9
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- Publication type:
- Article
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09277-9
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- Publication type:
- Article
CTD<sup>2</sup> Dashboard: a searchable web interface to connect validated results from the Cancer Target Discovery and Development Network.
- Published in:
- Database: The Journal of Biological Databases & Curation, 2017, v. 2017, n. 1, p. 1, doi. 10.1093/database/bax054
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- Publication type:
- Article
Rational Design of Orthogonal Receptor-Ligand Combinations.
- Published in:
- Angewandte Chemie International Edition, 1995, v. 34, n. 19, p. 2129, doi. 10.1002/anie.199521291
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- Publication type:
- Article
Combinatorial Synthesis and Multidimensional NMR Spectroscopy: An Approach to Understanding Protein-Ligand Interactions.
- Published in:
- Angewandte Chemie International Edition, 1995, v. 34, n. 9, p. 953, doi. 10.1002/anie.199509531
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- Publication type:
- Article
Natural Products as Probes of Cellular Function: Studies of Immunophilins.
- Published in:
- Angewandte Chemie International Edition, 1992, v. 31, n. 4, p. 384, doi. 10.1002/anie.199203841
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- Publication type:
- Article
On the Conformation and Structure of Organometal Complexes in the Solid State: Two Studies Relevant to Chemical Synthesis.
- Published in:
- Angewandte Chemie International Edition, 1990, v. 29, n. 3, p. 256, doi. 10.1002/anie.199002561
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- Publication type:
- Article
Development and validation of a T7 based linear amplification for genomic DNA.
- Published in:
- BMC Genomics, 2003, v. 4, p. 19, doi. 10.1186/1471-2164-4-19
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- Publication type:
- Article
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
- Published in:
- Nature, 2011, v. 475, n. 7355, p. 231, doi. 10.1038/nature10167
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- Publication type:
- Article
Organic chemistry: Molecular diversity by design.
- Published in:
- Nature, 2009, v. 457, n. 7226, p. 153, doi. 10.1038/457153a
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- Publication type:
- Article
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
- Published in:
- Nature, 2008, v. 452, n. 7184, p. 230, doi. 10.1038/nature06734
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- Publication type:
- Article
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.
- Published in:
- Angewandte Chemie, 2023, v. 135, n. 51, p. 1, doi. 10.1002/ange.202311924
- By:
- Publication type:
- Article
Modular Synthesis of Cyclopropane‐Fused N‐Heterocycles Enabled by Underexplored Diazo Reagents.
- Published in:
- Angewandte Chemie, 2022, v. 134, n. 38, p. 1, doi. 10.1002/ange.202203221
- By:
- Publication type:
- Article
A genetic basis for the variation in the vulnerability of cancer to DNA damage.
- Published in:
- Nature Communications, 2016, v. 7, n. 4, p. 11428, doi. 10.1038/ncomms11428
- By:
- Publication type:
- Article
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.
- Published in:
- Angewandte Chemie International Edition, 2023, v. 62, n. 51, p. 1, doi. 10.1002/anie.202311924
- By:
- Publication type:
- Article
Modular Synthesis of Cyclopropane‐Fused N‐Heterocycles Enabled by Underexplored Diazo Reagents.
- Published in:
- Angewandte Chemie International Edition, 2022, v. 61, n. 38, p. 1, doi. 10.1002/anie.202203221
- By:
- Publication type:
- Article
Ligand‐Enabled β‐Methylene C(sp<sup>3</sup>)−H Arylation of Masked Aliphatic Alcohols.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 20, p. 7783, doi. 10.1002/anie.202000632
- By:
- Publication type:
- Article
Fas Signal Transduction Triggers Either Proliferation or Apoptosis in Human Fibroblasts.
- Published in:
- Journal of Investigative Dermatology, 1997, v. 108, n. 2, p. 215, doi. 10.1111/1523-1747.ep12334273
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- Publication type:
- Article
1980s Camelot.
- Published in:
- 2019
- By:
- Publication type:
- Editorial
From Solution-Phase to Solid-Phase Enyne Metathesis: Crossover in the Relative Performance of Two Commonly Used Ruthenium Pre-Catalysts.
- Published in:
- Chemistry - A European Journal, 2005, v. 11, n. 17, p. 5086, doi. 10.1002/chem.200500279
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- Publication type:
- Article