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The APOE ε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.838436
By:
- Foley, Kate E.;
- Hewes, Amanda A.;
- Garceau, Dylan T.;
- Kotredes, Kevin P.;
- Carter, Gregory W.;
- Sasner, Michael;
- Howell, Gareth R.
Publication type:
Article
Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
Published in:
2022
By:
- Kotredes, Kevin P.;
- Oblak, Adrian;
- Pandey, Ravi S.;
- Lin, Peter Bor-Chian;
- Garceau, Dylan;
- Williams, Harriet;
- Uyar, Asli;
- O'Rourke, Rita;
- O'Rourke, Sarah;
- Ingraham, Cynthia;
- Bednarczyk, Daria;
- Belanger, Melisa;
- Cope, Zackary;
- Foley, Kate E.;
- Logsdon, Benjamin A.;
- Mangravite, Lara M.;
- Sukoff Rizzo, Stacey J.;
- Territo, Paul R.;
- Carter, Gregory W.;
- Sasner, Michael
Publication type:
Correction Notice
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
Published in:
Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.735524
By:
- Kotredes, Kevin P.;
- Oblak, Adrian;
- Pandey, Ravi S.;
- Lin, Peter Bor-Chian;
- Garceau, Dylan;
- Williams, Harriet;
- Uyar, Asli;
- O'Rourke, Rita;
- O'Rourke, Sarah;
- Ingraham, Cynthia;
- Bednarycek, Daria;
- Belanger, Melisa;
- Cope, Zackary;
- Foley, Kate E.;
- Logsdon, Benjamin A.;
- Mangravite, Lara M.;
- Sukoff Rizzo, Stacey J.;
- Territo, Paul R.;
- Carter, Gregory W.;
- Sasner, Michael
Publication type:
Article
In vivo validation of late‐onset Alzheimer's disease genetic risk factors.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 7, p. 4970, doi. 10.1002/alz.13840
By:
- Sasner, Michael;
- Preuss, Christoph;
- Pandey, Ravi S.;
- Uyar, Asli;
- Garceau, Dylan;
- Kotredes, Kevin P.;
- Williams, Harriet;
- Oblak, Adrian L.;
- Lin, Peter Bor‐Chian;
- Perkins, Bridget;
- Soni, Disha;
- Ingraham, Cindy;
- Lee‐Gosselin, Audrey;
- Lamb, Bruce T.;
- Howell, Gareth R.;
- Carter, Gregory W.
Publication type:
Article
Meeting report of the fifth annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer's Disease Research.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 7, p. 5035, doi. 10.1002/alz.13742
By:
- Sasner, Michael;
- Onos, Kristen D.;
- Territo, Paul R.;
- Sukoff Rizzo, Stacey J.
Publication type:
Article
Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 3987, doi. 10.1002/alz.13851
By:
- Pandey, Ravi S.;
- Arnold, Mattias;
- Batra, Richa;
- Krumsiek, Jan;
- Kotredes, Kevin P.;
- Garceau, Dylan;
- Williams, Harriet;
- Sasner, Michael;
- Howell, Gareth R.;
- Kaddurah‐Daouk, Rima;
- Carter, Gregory W.
Publication type:
Article
Characterizing molecular and synaptic signatures in mouse models of late‐onset Alzheimer's disease independent of amyloid and tau pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4126, doi. 10.1002/alz.13828
By:
- Kotredes, Kevin P.;
- Pandey, Ravi S.;
- Persohn, Scott;
- Elderidge, Kierra;
- Burton, Charles P;
- Miner, Ethan W.;
- Haynes, Kathryn A.;
- Santos, Diogo Francisco S.;
- Williams, Sean‐Paul;
- Heaton, Nicholas;
- Ingraham, Cynthia M.;
- Lloyd, Christopher;
- Garceau, Dylan;
- O'Rourke, Rita;
- Herrick, Sarah;
- Rangel‐Barajas, Claudia;
- Maharjan, Surendra;
- Wang, Nian;
- Sasner, Michael;
- Lamb, Bruce T.
Publication type:
Article
Gene replacement‐Alzheimer's disease (GR‐AD): Modeling the genetics of human dementias in mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 3080, doi. 10.1002/alz.13730
By:
- Benzow, Kellie;
- Karanjeet, Kul;
- Oblak, Adrian L.;
- Carter, Gregory W.;
- Sasner, Michael;
- Koob, Michael D.
Publication type:
Article
A novel 3D imaging method to establish baseline amyloid‐beta plaque load and analyze compound efficacy in pre‐clinical Alzheimer's disease animal models.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070759
By:
- Ferron, Gianna;
- Linehan, Stefan T;
- Ragan, Tim;
- Elk, Kevin J;
- Garceau, Dylan;
- Sasner, Michael
Publication type:
Article
Assessing the Role of PLCG2*M28L Risk In A Novel Mouse Model Late‐Onset Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079180
By:
- Territo, Paul R;
- Oblak, Adrian L;
- Persohn, Scott C;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Kotredes, Kevin P;
- Pandey, Ravi S;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R;
- Lamb, Bruce T
Publication type:
Article
Genetic diversity differentially regulates molecular mechanisms of brain aging under normal and pathological conditions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080755
By:
- Uyar, Asli;
- Onos, Kristen D;
- Keezer, Kelly J;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R
Publication type:
Article
Identifying human‐relevant genetic interactors of APOE using genetically diverse mouse strains.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080648
By:
- Onos, Kristen D;
- Elk, Kevin J;
- Uyar, Asli;
- Keezer, Kelly J;
- Marola, Olivia J;
- Kasper, Rachel;
- Pandey, Ravi S;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R
Publication type:
Article
Novel mouse models of late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078958
By:
- Sasner, Michael;
- Oblak, Adrian L;
- Pandey, Ravi S;
- Uyar, Asli;
- Garceau, Dylan;
- Kotredes, Kevin P;
- Soni, Disha;
- Lin, Peter Bor‐Chian;
- Ingraham, Cynthia;
- Lamb, Bruce T;
- Howell, Gareth R;
- Carter, Gregory W
Publication type:
Article
Elucidating the complex role of ABCA7 in late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078038
By:
- Howell, Gareth R;
- Kotredes, Kevin P;
- Pandey, Ravi S;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Lamb, Bruce T;
- Oblak, Adrian L;
- Territo, Paul R
Publication type:
Article
An Integrative Multi‐Omics Approach Reveals Molecular Signatures Associated with Age and High‐Fat Diet in Mouse Models of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077260
By:
- Pandey, Ravi S;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Haber, Annat;
- MahmoudianDehkordi, Siamak;
- Shantaraman, Anantharaman;
- Duong, Duc M.;
- Seyfried, Nicholas T;
- Kaddurah‐Daouk, Rima F.;
- Sasner, Michael;
- Howell, Gareth R;
- Oblak, Adrian L;
- Lamb, Bruce T;
- Carter, Gregory W
Publication type:
Article
Aging × Genetics × Environment: Characterization of Precision Disease Models for Preclinical Testing for Late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072778
By:
- Rizzo, Stacey J Sukoff;
- Haynes, Katy A;
- Santos, Diogo Francisco S.;
- Doolen, Suzanne;
- Williams, Sean‐Paul;
- Little, Gabriela;
- Reddy, Aman;
- Heaton, Nicholas;
- Hart, Jason T;
- Sasner, Michael;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Ingraham, Cynthia;
- Pandey, Ravi S;
- Preuss, Christoph;
- Uyar, Asli;
- Seyfried, Nicholas T;
- Territo, Paul R;
- Howell, Gareth R;
- Carter, Gregory W
Publication type:
Article
Leveraging MODEL‐AD mouse strains to understand the role of toxicant exposures on LOAD risk.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072777
By:
- Howell, Gareth R;
- Kotredes, Kevin P;
- Minaeva, Olga;
- Moncaster, Juliet A;
- Haber, Annat;
- Pandey, Ravi S;
- Rizzo, Stacey J Sukoff;
- Territo, Paul R;
- Lamb, Bruce T;
- Sasner, Michael;
- Oblak, Adrian L;
- Carter, Gregory W;
- Goldstein, Lee E
Publication type:
Article
A novel 3D imaging method to establish baseline amyloid‐beta plaque load and analyze compound efficacy in pre‐clinical Alzheimer's disease animal models.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081572
By:
- Ferron, Gianna;
- Linehan, Stefan T;
- Ragan, Tim;
- Elk, Kevin J;
- Garceau, Dylan;
- Sasner, Michael
Publication type:
Article
Genetic diversity differentially regulates molecular mechanisms of brain aging under normal and pathological conditions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080755
By:
- Uyar, Asli;
- Onos, Kristen D;
- Keezer, Kelly J;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R
Publication type:
Article
Identifying human‐relevant genetic interactors of APOE using genetically diverse mouse strains.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080648
By:
- Onos, Kristen D;
- Elk, Kevin J;
- Uyar, Asli;
- Keezer, Kelly J;
- Marola, Olivia J;
- Kasper, Rachel;
- Pandey, Ravi S;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R
Publication type:
Article
Novel mouse models of late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078958
By:
- Sasner, Michael;
- Oblak, Adrian L;
- Pandey, Ravi S;
- Uyar, Asli;
- Garceau, Dylan;
- Kotredes, Kevin P;
- Soni, Disha;
- Lin, Peter Bor‐Chian;
- Ingraham, Cynthia;
- Lamb, Bruce T;
- Howell, Gareth R;
- Carter, Gregory W
Publication type:
Article
Elucidating the complex role of ABCA7 in late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078038
By:
- Howell, Gareth R;
- Kotredes, Kevin P;
- Pandey, Ravi S;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Lamb, Bruce T;
- Oblak, Adrian L;
- Territo, Paul R
Publication type:
Article
An Integrative Multi‐Omics Approach Reveals Molecular Signatures Associated with Age and High‐Fat Diet in Mouse Models of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077260
By:
- Pandey, Ravi S;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Haber, Annat;
- MahmoudianDehkordi, Siamak;
- Shantaraman, Anantharaman;
- Duong, Duc M.;
- Seyfried, Nicholas T;
- Kaddurah‐Daouk, Rima F.;
- Sasner, Michael;
- Howell, Gareth R;
- Oblak, Adrian L;
- Lamb, Bruce T;
- Carter, Gregory W
Publication type:
Article
Aging × Genetics × Environment: Characterization of Precision Disease Models for Preclinical Testing for Late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072778
By:
- Rizzo, Stacey J Sukoff;
- Haynes, Katy A;
- Santos, Diogo Francisco S.;
- Doolen, Suzanne;
- Williams, Sean‐Paul;
- Little, Gabriela;
- Reddy, Aman;
- Heaton, Nicholas;
- Hart, Jason T;
- Sasner, Michael;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Ingraham, Cynthia;
- Pandey, Ravi S;
- Preuss, Christoph;
- Uyar, Asli;
- Seyfried, Nicholas T;
- Territo, Paul R;
- Howell, Gareth R;
- Carter, Gregory W
Publication type:
Article
Leveraging MODEL‐AD mouse strains to understand the role of toxicant exposures on LOAD risk.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072777
By:
- Howell, Gareth R;
- Kotredes, Kevin P;
- Minaeva, Olga;
- Moncaster, Juliet A;
- Haber, Annat;
- Pandey, Ravi S;
- Rizzo, Stacey J Sukoff;
- Territo, Paul R;
- Lamb, Bruce T;
- Sasner, Michael;
- Oblak, Adrian L;
- Carter, Gregory W;
- Goldstein, Lee E
Publication type:
Article
Meeting report of the annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer's Disease research.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 11, p. 5284, doi. 10.1002/alz.13093
By:
- Sasner, Michael;
- Territo, Paul R.;
- Sukoff Rizzo, Stacey J.
Publication type:
Article
Application of neurovascular uncoupling and whole brain network connectomics to assess the role of genetic and dietary risk factors in the LOAD2 mouse model.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065967
By:
- Silvola, Rebecca;
- Persohn, Scott C;
- Oblak, Adrian L;
- Lamb, Bruce T;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Howell, Gareth R;
- Sasner, Michael;
- Territo, Paul R
Publication type:
Article
A novel, humanized late‐onset Alzheimer's disease mouse model expressing APOEe4, Trem2*R47H, and amyloid‐beta.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064485
By:
- Kotredes, Kevin P;
- Oblak, Adrian L;
- Pandey, Ravi S;
- Territo, Paul R;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R;
- Lamb, Bruce T
Publication type:
Article
A novel whole‐brain imaging pipeline for high resolution spatial and temporal measurements of amyloid‐beta plaque dynamics in pre‐clinical Alzheimer's Disease animal models.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.064303
By:
- Ragan, Tim;
- Ferron, Gianna;
- Linehan, Stefan T;
- Sasner, Michael;
- Garceau, Dylan;
- Elk, Kevin J
Publication type:
Article
Genetically diverse mouse models of Alzheimer's Disease reveal an association between amyloid deposition and glycan metabolism in the brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.068076
By:
- Uyar, Asli;
- Elk, Kevin J;
- Garceau, Dylan;
- Bednarczyk, Daria;
- Sasner, Michael;
- Carter, Gregory W;
- Howell, Gareth R
Publication type:
Article
A clinically relevant mouse model of the Trem2*R47H Alzheimer's disease risk variant.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067173
By:
- Sasner, Michael;
- Oblak, Adrian L;
- Garceau, Dylan;
- Kotredes, Kevin P;
- Preuss, Christoph;
- Uyar, Asli;
- Pandey, Ravi S;
- Lin, Peter Bor‐Chian;
- Tsai, Andy Po‐Yi;
- Carter, Gregory W;
- Howell, Gareth R;
- Lamb, Bruce T
Publication type:
Article
Pharmacodynamics Assessment of Aducanumab in 5XFAD mice: A MODEL‐AD PTC Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.064606
By:
- Territo, Paul R;
- Quinney, Sara K;
- Masters, Andrea R;
- Haynes, Katy A;
- Cope, Zackery A;
- Little, Gabriela;
- Williams, Sean‐Paul;
- Meyer, Jill A;
- Peters, Jonathan;
- Figueiredo, Lucas;
- Persohn, Scott C;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Seyfried, Nicholas T.;
- Onos, Kristen D;
- Sasner, Michael;
- Howell, Gareth R;
- Carter, Gregory W;
- Oblak, Adrian L
Publication type:
Article
A more natural context: Variation in mouse background improves models of vascular contributions to Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.068069
By:
- Onos, Kristen D;
- Keezer, Kelly J;
- Uyar, Asli;
- Yang, Hongtian Stanley;
- Carter, Gregory W;
- Territo, Paul R;
- Walker, Ashley E;
- Patel, Hemal H;
- Sasner, Michael;
- Howell, Gareth R
Publication type:
Article
The role of Abca7 in late‐onset Alzheimer's disease animal models.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067665
By:
- Oblak, Adrian L;
- Kotredes, Kevin P;
- Ingraham, Cynthia;
- Territo, Paul R;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R;
- Lamb, Bruce T
Publication type:
Article
Comparative characterization of 5XFAD and hAbetaSAA mouse models of familial AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067648
By:
- Elk, Kevin J;
- Garceau, Dylan;
- Oblak, Adrian L;
- Pandey, Ravi S;
- Carter, Gregory W;
- Ferron, Gianna;
- Linehan, Stefan T;
- Ragan, Tim;
- Little, Gabriela;
- Williams, Sean‐Paul;
- Rizzo, Stacey J Sukoff;
- Lin, Sherry;
- Datta, Sandeep Robert;
- Sasner, Michael
Publication type:
Article
Deciphering the genetic interaction between klotho and APOE with novel mouse models.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.064175
By:
- Carter, Gregory W;
- Preuss, Christoph;
- Garceau, Dylan;
- Kotredes, Kevin P;
- Sasner, Michael
Publication type:
Article
Cerebral perfusion and glucose metabolism profiling reveal special phenotypes in the hAPOE3, hAPOE4, Trem2 risk, and doubled risks mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.063682
By:
- Lin, Peter Bor‐Chian;
- Persohn, Scott C;
- Bedwell, Amanda A;
- Jiang, Lei;
- Eldridge, Kierra;
- Speedy, Rachael;
- Kotredes, Kevin P;
- Pandey, Ravi S;
- Williams, Harriet M;
- Oblak, Adrian L;
- Sasner, Michael;
- Howell, Gareth R;
- Carter, Gregory W;
- Lamb, Bruce T;
- Territo, Paul R
Publication type:
Article
Incorporating genetic diversity to improve alignment of mouse models to human Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056498
By:
- Uyar, Asli;
- Garceau, Dylan;
- Bednarczyk, Daria;
- Sasner, Michael;
- Carter, Gregory W;
- Howell, Gareth R
Publication type:
Article
LOAD2: A late‐onset Alzheimer's disease mouse model expressing APOEε4, Trem2*R47H, and humanized amyloid‐beta.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056017
By:
- Kotredes, Kevin P;
- Oblak, Adrian L;
- Preuss, Christoph;
- Pandey, Ravi S;
- Territo, Paul R;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R;
- Lamb, Bruce T.
Publication type:
Article
Evaluation of late‐onset Alzheimer's disease risk variants in mouse models.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055629
By:
- Sasner, Michael;
- Oblak, Adrian L;
- Garceau, Dylan;
- Kotredes, Kevin P;
- Soni, Disha;
- Lin, Peter Bor‐Chian;
- Preuss, Christoph;
- Uyar, Asli;
- Pandey, Ravi S;
- Carter, Gregory W;
- Lamb, Bruce T.;
- Howell, Gareth R
Publication type:
Article
The synergistic role of high‐fat diet and genetic predisposition in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055514
By:
- Oblak, Adrian L;
- Kotredes, Kevin P;
- Reagan, Alaina M;
- Pandey, Ravi S;
- Sasner, Michael;
- Carter, Gregory W;
- Lamb, Bruce T.;
- Howell, Gareth R
Publication type:
Article
Differential splicing analyses of late‐onset AD models reveal alterations in neuronal genes associated with disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.052496
By:
- Pandey, Ravi S;
- Kotredes, Kevin P;
- Howell, Gareth R;
- Sasner, Michael;
- Carter, Gregory W
Publication type:
Article
A new set of mouse models to determine the role of the anti‐aging factor Klotho in late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051732
By:
- Preuss, Christoph;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Howell, Gareth R;
- Sasner, Michael;
- Carter, Gregory W
Publication type:
Article
Creating, characterizing, and validating the next generation of mouse models for late‐onset Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.049954
By:
- Carter, Gregory W;
- Howell, Gareth R;
- Lamb, Bruce T.;
- Oblak, Adrian L;
- Rizzo, Stacey J Sukoff;
- Sasner, Michael;
- Territo, Paul R
Publication type:
Article
The Alzheimer's disease protective R522 variant of PLCg2, consistently enhances PLCγ2 activation, depleting PI(4,5)P2 levels and altering cell function in in vitro and in vivo assays: Developing topics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047404
By:
- Philips, Thomas Ernest James;
- Maguire, Emily;
- Menzies, Georgina E;
- Sasner, Michael;
- Williams, Harriet M;
- Czubala, Magdalena;
- Evans, Neil;
- Cope, Emma L;
- Sims, Rebecca;
- Howell, Gareth;
- Lloyd‐Evans, Emyr;
- Williams, Julie;
- Allen, Nicholas D;
- Taylor, Philip
Publication type:
Article
N‐of‐1‐pathways transcriptomic analysis reveals distinct subtypes of Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046575
By:
- Uyar, Asli;
- Pandey, Ravi S.;
- Preuss, Christoph;
- Kotredes, Kevin P.;
- Oblak, Adrian L.;
- Logsdon, Benjamin A.;
- Rizzo, Stacey J. Sukoff;
- Howell, Gareth;
- Lamb, Bruce T.;
- Sasner, Michael;
- Carter, Gregory W.
Publication type:
Article
Deep phenotyping of the 5XFAD model: IU/JAX/PITT MODEL‐AD center: Development of new models and analysis methods/novel assays and technologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045981
By:
- Oblak, Adrian L.;
- Carter, Gregory W.;
- Howell, Gareth;
- Rizzo, Stacey J. Sukoff;
- Sasner, Michael;
- Territo, Paul R.;
- Ash, Carl T.;
- Ingraham, Cynthia;
- Kotredes, Kevin P.;
- Bleckert, Adam;
- Masek, Marissa;
- Patel, Neil;
- Chidambaram, Ritesh;
- Ragan, Tim;
- Lamb, Bruce T.
Publication type:
Article
Exercise as a strategy to prevent APOEε4‐dependent phenotypes: Genetics/genetic factors of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045887
By:
- Foley, Kate E.;
- Diemler, Cory;
- Garceau, Dylan;
- Moore, Annah M.;
- Hohman, Timothy J.;
- Sasner, Michael;
- Howell, Gareth
Publication type:
Article
Transcriptomic profiling of APOE4/Trem2*R47H mouse models for late‐onset Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045390
By:
- Pandey, Ravi S.;
- Kotredes, Kevin P.;
- Preuss, Christoph;
- Oblak, Adrian L.;
- Lamb, Bruce T.;
- Howell, Gareth;
- Sasner, Michael;
- Carter, Gregory W.
Publication type:
Article
Hallmarks of late‐onset Alzheimer's disease in a humanized mouse model: Development of new models and analysis methods/screening studies/platforms.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045162
By:
- Kotredes, Kevin P.;
- Preuss, Christoph;
- Pandey, Ravi S.;
- Territo, Paul R.;
- Oblak, Adrian L.;
- Kaddurah‐Daouk, Rima F.;
- Arnold, Matthias;
- Seyfried, Nicholas T.;
- Duong, Duc;
- Williams, Harriet M.;
- Lamb, Bruce T.;
- Rizzo, Stacey J. Sukoff;
- Carter, Gregory W.;
- Sasner, Michael;
- Howell, Gareth
Publication type:
Article

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