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- Title
Analyzing Nonmelanoma Skin Cancer Using Enzyme‐Activatable Two‐Photon Probes.
- Authors
Lim, Chang Su; Choi, Jee Woong; Kim, You Chan; Kim, Hwan Myung
- Abstract
Keywords: Nonmelanoma skin cancer; Squamous cell carcinoma; Two-photon microscopy; Enzyme activity EN Nonmelanoma skin cancer Squamous cell carcinoma Two-photon microscopy Enzyme activity 103 106 4 01/29/21 20210101 NES 210101 GLO:1CJF/01jan21:bkcs12150-toc-0001.jpg PHOTO (COLOR): . gl In this study, we attempted to diagnose nonmelanoma skin cancer (NMSC) more accurately by two-photon microscopy imaging deep inside of skin tissue using a two-photon probes that can detect three enzyme activities. Nonmelanoma skin cancer (NMSC) is the most common skin cancer and is composed of basal cell carcinoma (BCC) with a relatively low risk of metastasis and squamous cell carcinoma (SCC). In normal tissues, the ratio value was 0.56 ± 0.081, which was larger than that of SCC lesion tissue (0.44 ± 0.089).
- Subjects
SKIN cancer; BOWEN'S disease
- Publication
Bulletin of the Korean Chemical Society, 2021, Vol 42, Issue 1, p103
- ISSN
0253-2964
- Publication type
Article
- DOI
10.1002/bkcs.12150