We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Improvement of Quality of Life with Shenfu Injection in Non Small Cell Lung Cancer Patients Treated with Gemcitabine plus Cisplatin Regimen.
- Authors
Wu Wan-Yin; Long Shun-Qin; Zhang Hal-Bo; Chai Xiao-Shu; Deng Hong; Xue Xiao-Guang; Wang Bin; Luo Hai-Ying; Liu Wei-Sheng
- Abstract
Objective: To observe the effect of Shenfu injection (SFI) in treating non small cell lung cancer (NSCLC) patients on quality of life with gemcitabine (GEM) plus cisplatin (GP) regimen. Methods: Thirty-four patients were ready to receive GP regimen chemotherapy for treating NSCLC disease, according to lot-drawing, they were divided into SFI pre-treatmeat group (18 cases) and SFI post-treatment group (16 cases). SFI pre-treatment group: During the first treatment course, chemotherapy was begun with SFI 60 ml, intravenous dripping on the 3rd day. once daily, consecutively for 10 days; on the 1st day, GP regimen (GEM 1250 mg/m², intravenous dripping, on the 1st and 8th day; cisplatin 70 mg/m² on the 2nd day; 21 days as one cycle) was carried out: in the second treatment course GP regimen was merely given to serve as the self-control. SFI post-treatment group: the medicament sequence order was reversed from that of pre-treatment group, Using dual international quality of life (QOL) scores, the effect of SFI on the patients QOL was observed through randomized self pre- and post- crossover control. Results: The QOL in the 34 patients after being treated by SFI in combination with GP chemotherapy regimen in one group, and GP chemotherapy regimen alone in the other, was improved in different degrees, with significant difference (P<0.01); comparision of SFI combined with GP chemotherapy regimen with GP chemotherapy alone showed that QOL in patients was significantly different (P<0.01). Conclusion= SFI could improve QOL in patients with NSCLC who were treated with GP regimen.
- Subjects
INJECTIONS; SMALL cell lung cancer; QUALITY of life; CISPLATIN; CANCER patients; CANCER treatment
- Publication
Chinese Journal of Integrative Medicine, 2006, Vol 12, Issue 1, p50
- ISSN
1672-0415
- Publication type
Article
- DOI
10.1007/BF02857431