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- Title
N-terminal pro-brain natriuretic peptide from fresh urine for the biochemical detection of heart failure and left ventricular dysfunction.
- Authors
Jungbauer, Carsten G.; Buchner, Stefan; Birner, Christoph; Resch, Markus; Heinicke, Norbert; Debl, Kurt; Buesing, Monika; Biermeier, Daniela; Schmitz, Gerd; Riegger, Günter; Luchner, Andreas
- Abstract
Aims: Plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) is a strong biochemical marker of heart failure and left ventricular dysfunction (LVD). Due to renal arterio-venous clearance of NT-proBNP and the correlation of plasma concentrations with renal function, we hypothesized that NT-proBNP may have potential as a urinary marker. The objective of this study was to assess urinary concentrations of NT-proBNP and to identify the predictive value of urinary NT-proBNP for detecting LVD and heart failure.
- Subjects
ATRIAL natriuretic peptides; HEART failure; HEART diseases; BIOMARKERS; CARDIOVASCULAR diseases
- Publication
European Journal of Heart Failure, 2010, Vol 12, Issue 4, p331
- ISSN
1388-9842
- Publication type
Article
- DOI
10.1093/eurjhf/hfq016