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- Title
Paediatric kidney transplants from donors aged 1 year and under: an analysis of the Australian and New Zealand Dialysis and Transplant Registry from 1963 to 2018.
- Authors
Yao, Jinna; Clayton, Philip A.; Wyburn, Kate; Choksi, Harsham; Cavazzoni, Elena; Tovmassian, David; Lau, Howard M. H.; Allen, Richard; Yuen, Lawrence; Laurence, Jerome M.; Lam, Vincent W. T.; Pleass, Henry C. C.
- Abstract
Summary: Kidneys from very small donors have the potential to significantly expand the donor pool. We describe the collective experience of transplantation using kidneys from donors aged ≤1 year in Australian and New Zealand. The ANZDATA registry was analysed on all deceased donor kidney transplants from donors aged ≤1 year. We compared recipient characteristics and outcomes between 1963–1999 and 2000–2018. From 1963 to 1999, 16 transplants were performed [9 (56%) adults, 7 (44%) children]. Death‐censored graft survival was 50% and 43% at 1 and 5 years, respectively. Patient survival was 90% and 87% at 1 and 5 years, respectively. From 2000 to 2018, 26 transplants were performed [25 (96%) adults, 1 (4%) children]. Mean creatinine was 73 µmol/l ±49.1 at 5 years. Death‐censored graft survival was 85% at 1 and 5 years. Patient survival was 100% at 1 and 5 years. Thrombosis was the cause of graft loss in 12% of recipients in the first era from 1963 to 1999, and 8% of recipients in the second era from 2000 to 2018. We advocate the judicious use of these small paediatric grafts from donors ≤1 year old. Optimal selection of donor and recipients may lead to greater acceptance and success of transplantation from very young donors.
- Subjects
NEW Zealand; KIDNEY transplantation; TRANSPLANTATION of organs, tissues, etc.; SURGICAL complications; AUSTRALIANS; AGE
- Publication
Transplant International, 2021, Vol 34, Issue 1, p118
- ISSN
0934-0874
- Publication type
Article
- DOI
10.1111/tri.13772