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- Title
1,2,4-TRIAZOLES AS INTERMEDIATES FOR THE SYNTHESIS OF HYBRID MOLECULES.
- Authors
ŞERBAN, GEORGETA
- Abstract
This paper aim was to present some new heterocyclic compounds from the class of 1,2,4-triazole-3-thione which have been synthesized by intramolecular cyclization of the corresponding thiosemicarbazides with ammonia. 4-R-1-cyanoacetylthiosemicarbazides were obtained by nucleophilic addition of cyanoacetic acid hydrazide to different isothiocyanates. The structures of the newly synthesized compounds were elucidated by spectral data and elemental analysis.
- Subjects
TRIAZOLES synthesis; HETEROCYCLIC compounds; ISOTHIOCYANATES; RING formation (Chemistry); NUCLEOPHILIC addition (Chemistry); HYDRAZIDES
- Publication
Farmacia, 2016, Vol 64, Issue 4, p549
- ISSN
0014-8237
- Publication type
Article