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- Title
Non‐Hodgkin lymphoma presenting as acute pancreatitis: A rare occurrence.
- Authors
Pitlick, Mitchell M.; Abeykoon, Jithma P.; Dao, Linda N.; Thompson, Carrie A.
- Abstract
Key Clinical Message: Lymphoma often presents with extranodal manifestations. However, pancreatic involvement resulting in pancreatitis is rare. CD20‐negative variants of diffuse large B‐cell lymphoma are also rare and are more likely to present with extranodal involvement. Lymphoma should be considered in patients presenting with pancreatitis without traditional risk factors. F18‐FDG PET and renal biopsy findings consistent with diffuse large B‐cell lymphoma. A: Widespread abdominal organ involvement prior to therapy. B: Significant interval improvement in disease burden after 2 cycles of CHOP. C: Kidney mass biopsy showing lymphoid cells with large nuclei, irregular nuclear contours, prominent nucleoli and modest amounts of cytoplasm (white arrow) with scattered forms containing very large, pleomorphic nuclei (black arrow) (hematoxylin & eosin stain, 100x). D: Tumor cells positive for CD79a (white arrow) (CD79a immunostain, 100x).
- Subjects
PANCREATITIS; CELL nuclei; DIFFUSE large B-cell lymphomas; CYTOPLASM; EOSIN; BIOPSY
- Publication
Clinical Case Reports, 2019, Vol 7, Issue 1, p107
- ISSN
2050-0904
- Publication type
Article
- DOI
10.1002/ccr3.1885