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- Title
Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report.
- Authors
Uchida, Naohiro; Tsuji, Seijiro; Fujita, Kohei; Koizumi, Mitsuteru; Moriyoshi, Koki; Mio, Tadashi
- Abstract
Key Clinical Message: In the treatment of immunotherapy with immune checkpoint inhibitors, we often experience immune‐related adverse event which manifest most frequently as a skin disorder, and very rarely as a renal disorder. In our manuscript, we report the case of a 71‐year‐old man with nivolumab‐induced severe acute kidney injury (AKI) in which the time from treatment initiation to the onset of AKI was the longest among the previously reported cases (377 days). Prolonged follow‐up is therefore warranted to detect late‐onset AKI. In the treatment of immunotherapy with immune checkpoint inhibitors, we often experience immune‐related adverse event which manifest most frequently as a skin disorder, and very rarely as a renal disorder. In our manuscript, we report the case of a 71‐year‐old man with nivolumab‐induced severe acute kidney injury (AKI) in which the time from treatment initiation to the onset of AKI was the longest among the previously reported cases (377 days). Prolonged follow‐up is therefore warranted to detect late‐onset AKI.
- Subjects
ACUTE kidney failure; NON-small-cell lung carcinoma; IMMUNOTHERAPY; IMMUNE response; SKIN disease diagnosis
- Publication
Clinical Case Reports, 2018, Vol 6, Issue 11, p2185
- ISSN
2050-0904
- Publication type
Case Study
- DOI
10.1002/ccr3.1848