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- Title
Prevalence of acromegaly in moderate‐to‐severe obstructive sleep apnoea.
- Authors
Bruyneel, Marie; Veltri, Flora; Sitoris, Georgiana; Vintila, Sabina; Truffaut, Laurent; Kleynen, Pierre; Poppe, Kris G.
- Abstract
However, the systematic measurement of IGF-1 might not be the most optimal cost-benefit approach to detect AM and, therefore, novel techniques to detect AM are urgently needed. Since these clinical features are the fundamental ones of AM patients, physicians taking care of OSAS patients should be trained to recognize acral enlargement features. Features at diagnosis of 324 patients with acromegaly did not change from 1981 to 2006: acromegaly remains under-recognized and under- diagnosed. Keywords: acromegaly; diabetes mellitus type 2; hypertension; obstructive sleep apnea; pituitary; sleep disordered breathing EN acromegaly diabetes mellitus type 2 hypertension obstructive sleep apnea pituitary sleep disordered breathing 918 921 4 05/05/22 20220601 NES 220601 To the Editor Acromegaly (AM) is an endocrine disorder in which the tongue is enlarged and, therefore, is a risk factor for obstructive sleep apnoea syndrome (OSAS).1 OSAS is detected in 26 to 70% of AM patients and results mainly from pharyngeal soft tissue swelling and maxillo-mandibular bones overgrowth.2 However, data on the prevalence of AM in patients with OSAS remain scarce, reporting prevalence's between 0.14% and 0.35%,3-5 significantly higher than those in the general population (0.003%-0.014%).6 Guidelines on OSAS management do not propose systematic screening for the presence of AM.7 The aim of our study was to investigate the prevalence of AM in patients with moderate-to-severe OSAS and to compare our findings to the prevalence of AM in the general population.
- Subjects
ACROMEGALY; SLEEP apnea syndromes; TYPE 2 diabetes
- Publication
Clinical Endocrinology, 2022, Vol 96, Issue 6, p918
- ISSN
0300-0664
- Publication type
Article
- DOI
10.1111/cen.14463