We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
IMPACT OF EXERCISE TRAINING AT DIFFERENT INTENSITY LEVELS ON CARDIAC FUNCTION AND EXERCISE CAPACITY IN PATIENTS WITH CHRONIC HEART FAILURE: A PROSPECTIVE COHORT STUDY.
- Authors
Zhenying ZHANG; Lizhong WANG; Jianing XI; Xiaojing SUN; Xingguo SUN
- Abstract
Objective: To investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Methods: This prospective cohort study enrolled patients with chronic heart failure at Beijing Rehabilitation Hospital, Beijing, China from January 2018 to January 2020. Participants received conventional therapy (non-exercise group) or therapy plus cycle ergometer exercises at an intensity of 80% anaerobic threshold (EA group) and Δ50% power above anaerobic threshold (EB group) for 12 weeks. The primary outcome was peak oxygen uptake. Results: Forty-five patients (15/group) completed the study without serious complications. Exercise training at an intensity of Δ50% power above anaerobic threshold had better effects on exercise capacity than exercise at an intensity of 80% anaerobic threshold, as shown by a greater improvement in peak oxygen uptake (20.3 ± 4.1 vs 16.8 ± 3.2 mL/min/kg), peak O2 pulse (12.5 ± 2.3 vs 10.1 ± 2.1 mL/beat), and peak workload (123.1 ± 26.9 vs 102.8 ± 29.5 W) in patients with chronic heart failure (all p < 0.001). Exercise improved the 6-min walk test distance (control: 394.0 ± 74.1; EA: 481.4 ± 89.4; EB: 508.9 ± 92.5 m; p < 0.001) and health-related quality of life (control: 40.7 ± 12.3; EA: 16.2 ± 8.6; EB: 11.5 ± 6.4; p < 0.001). Conclusion: Compared with an intensity of 80% anaerobic threshold, exercise training at an intensity of Δ 50% power above anaerobic threshold was safe and had better effects on cardiac function, exercise capacity, and health-related quality of life.
- Subjects
CHINA; HEART failure treatment; HEART physiology; AEROBIC capacity; ECHOCARDIOGRAPHY; LEFT heart ventricle; STATISTICS; REHABILITATION centers; ONE-way analysis of variance; EXERCISE physiology; FISHER exact test; TREATMENT effectiveness; T-test (Statistics); EXERCISE intensity; QUALITY of life; EMPLOYEES' workload; DESCRIPTIVE statistics; ENZYME-linked immunosorbent assay; RESEARCH funding; QUESTIONNAIRES; PEPTIDE hormones; DATA analysis software; BIOMECHANICS; DATA analysis; EXERCISE therapy; LONGITUDINAL method; ANAEROBIC threshold; PULSE (Heart beat)
- Publication
Journal of Rehabilitation Medicine (Stiftelsen Rehabiliteringsinformation), 2022, Vol 54, p1
- ISSN
1650-1977
- Publication type
Article
- DOI
10.2340/jrm.v54.1023