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Hyperpolarized δ-[1- <sup>13</sup>C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32463-1
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- Publication type:
- Article
Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.
- Published in:
- Metabolites (2218-1989), 2021, v. 11, n. 2, p. 109, doi. 10.3390/metabo11020109
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- Publication type:
- Article
Acquisition and quantification pipeline for in vivo hyperpolarized <sup>13</sup>C MR spectroscopy.
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- Magnetic Resonance in Medicine, 2022, v. 87, n. 4, p. 1673, doi. 10.1002/mrm.29081
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- Publication type:
- Article
Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing.
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- Magnetic Resonance in Medicine, 2016, v. 76, n. 2, p. 369, doi. 10.1002/mrm.26272
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- Publication type:
- Article
Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized <sup>13</sup>C metabolites.
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- Magnetic Resonance in Medicine, 2015, v. 74, n. 3, p. 622, doi. 10.1002/mrm.25422
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- Publication type:
- Article
Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma.
- Published in:
- Scientific Reports, 2017, p. 44792, doi. 10.1038/srep44792
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- Publication type:
- Article
Detection of inflammatory cell function using <sup>13</sup>C magnetic resonance spectroscopy of hyperpolarized [6-<sup>13</sup>C]-arginine.
- Published in:
- Scientific Reports, 2016, p. 31397, doi. 10.1038/srep31397
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- Publication type:
- Article
Metabolic Reprogramming in Mutant IDH1 Glioma Cells.
- Published in:
- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118781
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- Publication type:
- Article
Glioma Cells with the IDH1 Mutation Modulate Metabolic Fractional Flux through Pyruvate Carboxylase.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108289
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- Publication type:
- Article
Early Chk1 Phosphorylation Is Driven by Temozolomide-Induced, DNA Double Strand Break- and Mismatch Repair-Independent DNA Damage
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062351
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- Publication type:
- Article
HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells.
- Published in:
- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062610
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- Publication type:
- Article
Pyruvate Kinase M2 Expression, but Not Pyruvate Kinase Activity, Is Up-Regulated in a Grade-Specific Manner in Human Glioma.
- Published in:
- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057610
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- Publication type:
- Article
Magnetic Resonance Spectroscopy Detectable Metabolomic Fingerprint of Response to Antineoplastic Treatment.
- Published in:
- PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026155
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- Publication type:
- Article
HDAC inhibition in glioblastoma monitored by hyperpolarized <sup>13</sup>C MRSI.
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- NMR in Biomedicine, 2019, v. 32, n. 1, p. N.PAG, doi. 10.1002/nbm.4044
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- Publication type:
- Article
HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer.
- Published in:
- NMR in Biomedicine, 2014, v. 27, n. 11, p. 1361, doi. 10.1002/nbm.3198
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- Publication type:
- Article
MR-detectable metabolic consequences of mitogen-activated protein kinase kinase (MEK) inhibition.
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- NMR in Biomedicine, 2014, v. 27, n. 6, p. 700, doi. 10.1002/nbm.3109
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- Publication type:
- Article
Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells.
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- NMR in Biomedicine, 2013, v. 26, n. 3, p. 299, doi. 10.1002/nbm.2848
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- Publication type:
- Article
Vascular patterning and permeability in prostate cancer models with differing osteogenic properties.
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- NMR in Biomedicine, 2012, v. 25, n. 6, p. 843, doi. 10.1002/nbm.1800
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- Publication type:
- Article
Metabolic consequences of treatment with AKT inhibitor perifosine in breast cancer cells.
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- NMR in Biomedicine, 2012, v. 25, n. 2, p. 379, doi. 10.1002/nbm.1764
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- Publication type:
- Article
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
- Published in:
- 2011
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- Publication type:
- journal article
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized.
- Published in:
- Journal of Magnetic Resonance Imaging, 2011, v. 33, n. 6, p. 1284, doi. 10.1002/jmri.22563
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- Publication type:
- Article
Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.
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- 2003
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- Publication type:
- journal article
Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Heat Shock Protein 90 Inhibitor 17-Allylamino,17-Demethoxygeldanamycin (17AAG) in Human Color Cancer Models.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 21, p. 1624, doi. 10.1093/jnci/djg084
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- Publication type:
- Article
Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.
- Published in:
- Cancer & Metabolism, 2018, v. 6, p. 1, doi. 10.1186/s40170-018-0178-3
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- Publication type:
- Article
In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63160-y
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- Publication type:
- Article
PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47021-x
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- Publication type:
- Article
Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-<sup>13</sup>C]gluconolactone.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.589570
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- Publication type:
- Article
Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
- Published in:
- Neuro-Oncology, 2021, v. 23, n. 9, p. 1509, doi. 10.1093/neuonc/noab093
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- Publication type:
- Article
METABOLIC IMAGING BIOMARKERS FOR MUTANT IDH1 GLIOMAS.
- Published in:
- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii12, doi. 10.1093/neuonc/nou206.41
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- Publication type:
- Article
Lactate dehydrogenase A silencing in IDH mutant gliomas.
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- Neuro-Oncology, 2014, v. 16, n. 5, p. 686, doi. 10.1093/neuonc/not243
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- Publication type:
- Article
Longitudinal evaluation of MPIO-labeled stem cell biodistribution in glioblastoma using high resolution and contrast-enhanced MR imaging at 14.1Tesla.
- Published in:
- Neuro-Oncology, 2012, v. 14, n. 8, p. 1050, doi. 10.1093/neuonc/nos126
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- Publication type:
- Article
Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
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- Neuro-Oncology, 2012, v. 14, n. 3, p. 315, doi. 10.1093/neuonc/nor209
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- Publication type:
- Article
Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma.
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- Neuro-Oncology, 2010, v. 12, n. 6, p. 559, doi. 10.1093/neuonc/nop058
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- Publication type:
- Article
Molecular imaging of Metabolic Reprograming in Mutant IDH Cells.
- Published in:
- Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00060
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- Publication type:
- Article
Non-invasive in vivo assessment of IDH1 mutational status in glioma.
- Published in:
- Nature Communications, 2013, v. 4, n. 9, p. 2429, doi. 10.1038/ncomms3429
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- Publication type:
- Article
Magnetic Resonance (MR) Metabolic Imaging in Glioma.
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- 2015
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- Publication type:
- Other
Monitoring response to a clinically relevant IDH inhibitor in glioma—Hyperpolarized <sup>13</sup>C magnetic resonance spectroscopy approaches.
- Published in:
- Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad143
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- Publication type:
- Article
Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D <sup>13</sup>C magnetic resonance spectroscopic imaging.
- Published in:
- Magnetic Resonance in Medicine, 2013, v. 70, n. 1, p. 33, doi. 10.1002/mrm.24434
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- Publication type:
- Article
Macromolecular dynamic contrast-enhanced (DCE)-MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti-platelet-derived growth factor receptor (PDGFR) therapy, indicating a drop in vascular endothelial growth factor receptor (VEGFR) activation
- Published in:
- Magnetic Resonance in Medicine, 2008, v. 60, n. 4, p. 822, doi. 10.1002/mrm.21727
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- Publication type:
- Article
The application of <sup>13</sup>C NMR to the characterization of phospholipid metabolism in cells.
- Published in:
- Magnetic Resonance in Medicine, 1992, v. 25, n. 2, p. 384, doi. 10.1002/mrm.1910250219
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- Publication type:
- Article
In vivo investigation of hyperpolarized [1,3-<sup>13</sup>C<sub>2</sub>]acetoacetate as a metabolic probe in normal brain and in glioma.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39677-2
- By:
- Publication type:
- Article
Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
- Published in:
- Neuro-Oncology, 2022, v. 24, n. 11, p. 1898, doi. 10.1093/neuonc/noac112
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- Publication type:
- Article
Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.
- Published in:
- Neuro-Oncology, 2022, v. 24, n. 7, p. 1101, doi. 10.1093/neuonc/noac022
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- Publication type:
- Article
Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy Method.
- Published in:
- Molecular Imaging, 2008, v. 7, n. 2, p. 92, doi. 10.2310/7290.2008.0011
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- Publication type:
- Article
Choline metabolism in malignant transformation.
- Published in:
- 2011
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- Publication type:
- journal article
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20312-y
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- Publication type:
- Article
Treatment of SW620 Cells with Tomudex and Oxaliplatin Induces Changes in 2-Deoxy-D-Glucose Incorporation Associated with Modifications in Glucose Transport.
- Published in:
- Journal of Nuclear Medicine, 2000, v. 41, n. 10, p. 1753
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- Publication type:
- Article