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- Title
Volumetric MRI of the lungs during forced expiration.
- Authors
Berman, Benjamin P.; Pandey, Abhishek; Li, Zhitao; Jeffries, Lindsie; Trouard, Theodore P.; Oliva, Isabel; Cortopassi, Felipe; Martin, Diego R.; Altbach, Maria I.; Bilgin, Ali
- Abstract
Purpose Lung function is typically characterized by spirometer measurements, which do not offer spatially specific information. Imaging during exhalation provides spatial information but is challenging due to large movement over a short time. The purpose of this work is to provide a solution to lung imaging during forced expiration using accelerated magnetic resonance imaging. The method uses radial golden angle stack-of-stars gradient echo acquisition and compressed sensing reconstruction. Methods A technique for dynamic three-dimensional imaging of the lungs from highly undersampled data is developed and tested on six subjects. This method takes advantage of image sparsity, both spatially and temporally, including the use of reference frames called bookends. Sparsity, with respect to total variation, and residual from the bookends, enables reconstruction from an extremely limited amount of data. Results Dynamic three-dimensional images can be captured at sub-150 ms temporal resolution, using only three (or less) acquired radial lines per slice per timepoint. The images have a spatial resolution of
- Publication
Magnetic Resonance in Medicine, 2016, Vol 75, Issue 6, p2295
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.25798