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- Title
The Impact of Comorbidity on Cognitive-Behavioral Therapy Response in Youth with Anxiety and Autism Spectrum Disorder.
- Authors
McBride, Nicole M.; Weinzimmer, Saira A.; La Buissonnière-Ariza, Valérie; Schneider, Sophie C.; Ehrenreich May, Jill; Lewin, Adam B.; McGuire, Joseph F.; Goodman, Wayne K.; Wood, Jeffrey J.; Storch, Eric A.
- Abstract
The impact of externalizing comorbidity on treatment outcome was examined in 104 youth ages 7-16 (M = 11.09 years) with autism spectrum disorder and primary anxiety/obsessive compulsive disorder who completed modular cognitive behavioral therapy (CBT) for anxiety/OCD. Three comorbidity profiles were utilized for group comparisons: participants with oppositional defiant or conduct disorder with attention-deficit hyperactivity disorder (ODD; CD; ADHD; group EXT, n = 25); those without ODD/CD and only ADHD (group ADHD, n = 46); and those without externalizing comorbidity (NO-EXT, n = 33). Post-treatment outcomes were measured continuously (Pediatric Anxiety Rating Scale, Clinical Global Impression-Severity) and categorically (treatment response, remission). The ADHD group was four times more likely of being a treatment responder compared to NO-EXT (OR 4.05). Comorbidity group did not impact remission. After controlling for pre-treatment scores, there was a significantly greater reduction of the CGI-S for ADHD versus NO-EXT and EXT versus NO-EXT, but results did not significantly differ for the PARS. Results suggest that a modular CBT approach yields positive impact for treatment outcomes in youth with comorbid externalizing problems, particularly among those with comorbid ADHD.
- Subjects
AUTISM spectrum disorders; COGNITIVE therapy; OPPOSITIONAL defiant disorder in children; ATTENTION-deficit hyperactivity disorder; OBSESSIVE-compulsive disorder; COMORBIDITY; ANXIETY treatment; ANXIETY disorders treatment; RESEARCH; RESEARCH methodology; EVALUATION research; TREATMENT effectiveness; COMPARATIVE studies; CHILD psychopathology; RESEARCH funding; ANXIETY; ANXIETY disorders; LONGITUDINAL method; DISEASE complications; PSYCHOSOCIAL factors
- Publication
Child Psychiatry & Human Development, 2020, Vol 51, Issue 4, p625
- ISSN
0009-398X
- Publication type
journal article
- DOI
10.1007/s10578-020-00961-2