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- Title
Synthesis, Crystal Structure, Electrochemical Properties, and Biological Activity of 2-((1H-Benzimidazol-2-yl)methylamino)acetic Acid.
- Authors
Sabithakala, T.; Bhargavi, G.; Venkata Ramana Reddy, Ch.
- Abstract
A water soluble compound, (2-((1H-benzimidazol-2-yl)methylamino)acetic acid, BIGH, has been synthesized and structurally characterized by elemental analysis, IR and UV spectroscopies, 1H-NMR, thermogravimetric and differential thermal analyses, and single crystal and powder X-ray diffraction. BIGH can act as a flexible planar ligand with three potential coordination sites. It crystallizes in a monoclinic system with the sp. gr. P21/c with the unit cell parameters, a = 9.3764(7) Å, b = 11.5031(8) Å, c = 10.0543(6) Å, and Z = 4. The crystal structure was stabilized through inter-molecular hydrogen bonds. The anti-microbial activity of the compound has been studied against Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus, which showed a good activity against Bacillus subtilis. Cyclic voltammogram of the compound shows that it is a redox-active molecule.
- Subjects
BENZIMIDAZOLES; CRYSTAL structure; ELECTROCHEMICAL analysis; ACETIC acid; SOLUBILITY
- Publication
Crystallography Reports, 2018, Vol 63, Issue 4, p600
- ISSN
1063-7745
- Publication type
Article
- DOI
10.1134/S1063774518040235