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- Title
The role of Notch signaling during hematopoietic lineage commitment.
- Authors
Radtke, Freddy; Wilson, Anne; Ernst, Bettina; MacDonald, H. Robson
- Abstract
Summarizes several findings of studies and controversies regarding the role of Notch signaling in the myeloid and lymphoid systems. Expression of Notch function in early hematopoiesis; Role of Notch signaling in thymocyte development; Influence of Notch function in the activation and tolerance of T cells during antigen recognition.
- Subjects
NOTCH genes; LYMPHOID tissue; HEMATOPOIESIS; T cells; IMMUNE recognition
- Publication
Immunological Reviews, 2002, Vol 187, Issue 1, p65
- ISSN
0105-2896
- Publication type
Article
- DOI
10.1034/j.1600-065X.2002.18706.x