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- Title
Relationship between Giant Negative T-Wave and Severity of Apical Hypertrophy in Patients with Apical Hypertrophic Cardiomyopathy.
- Authors
Park, Sun-Yi; Park, Tae-Ho; Kim, Jung-Hwan; Baek, Hee-Kyung; Seo, Jeong-Min; Kim, Woo-Jae; Cha, Kwang-Soo; Kim, Moo-Hyun; Kim, Young-Dae
- Abstract
Objectives: This study was aimed at evaluating the usefulness of giant negative T-wave (GNT) as an index of apical hypertrophic cardiomyopathy (ACM) severity and as a better echocardiographic index to represent apical hypertrophy. Methods: Seventy-five patients who were recently diagnosed with ACM by echocardiography were enrolled in this study. ACM patients were divided into two groups: group 1 (ACM with GNT) and group 2 (ACM without GNT). To evaluate ACM severity, apical wall thickness (A-WT) and apical cross-sectional muscle area (A-CSMA) were measured by echocardiography. Results: Twenty-seven patients (36%) had GNT. The maximal A-WT of groups 1 and 2 was 19.7 ± 2.4 and 18.6 ± 2.0 mm, P = 0.027, respectively. In addition, the maximal A-CSMA differed significantly between groups 1 and 2 (14.2 ± 1.8 vs. 11.8 ± 1.9 cm2, P < 0.001). In the correlation analysis, Tmax showed a stronger correlation with A-CSMA than with A-WT (r = 0.599 vs. r = 0.291). Conclusions: These results indicate that the presence of GNT in ACM patients may represent more severe apical hypertrophy. Furthermore, A-CSMA may be a more reliable ACM severity index than A-WT. (Echocardiography 2010;27:770-776)
- Subjects
HYPERTROPHIC cardiomyopathy; ANALYSIS of variance; CARDIAC output; COMPUTER software; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; LEFT heart ventricle; HEART beat; MYOCARDIUM; RESEARCH evaluation; RESEARCH funding; STATISTICS; T-test (Statistics); DATA analysis; INTER-observer reliability; SEVERITY of illness index; DISEASE complications; PATHOLOGICAL physiology; DIAGNOSIS
- Publication
Echocardiography, 2010, Vol 27, Issue 7, p770
- ISSN
0742-2822
- Publication type
Article
- DOI
10.1111/j.1540-8175.2010.01152.x