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- Title
P3: Molecular detection of hepatitis B virus DNA in ovarian carcinoma in Morocco.
- Authors
Benhessou, Mustapha; Assoumou, Samira Zoa; Boumba, Anicet Luc M.; Benchkrroun, Mohammed Nabil; Bouhya, Said; Ennaji, My Mustapha
- Abstract
Background: Epithelial ovarian cancer (EOC) is a major gynecological problem in Morocco represents more than 70% of ovarian cancers. Its etiology remains poorly understood. This study aimed to determine the presence of HBV-DNA in fresh EOC specimens from Moroccan patients. Materials and Methods: HBV-DNA was examined from DNA extracts of 50 fresh biopsies specimens from patients with histologically proven EOC by using PCR method. Results: HBV-DNA was found to be positive in four patients (8%). All of the positive patients had serous adenocarcinoma (10.3%) and advanced stage disease. Conclusion: The results of this study suggest that hepatitis B virus may be involved in the etiology of ovarian cancer.
- Subjects
OVARIAN cancer; HEPATITIS B virus; MOLECULAR oncology
- Publication
Clinical Cancer Investigation Journal, 2015, Vol 4, Issue S1, pS22
- ISSN
2278-1668
- Publication type
Abstract