We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Acute Kidney Injury - Definition and Classification.
- Authors
Kellum, John A.; Srisawat, Nattachai
- Abstract
Acute kidney injury (AKI) is a common clinical syndrome defined as a sudden onset of reduced kidney function manifest by increased serum creatinine or a reduction in urine output. This clinical syndrome is known by 25 names and has at least 35 definitions. As a result of this deficiency of standardised definition, reported incidences of AKI in intensive care units range from 1 to 25%, with mortality rates between 15 and 60%. This lack of a uniform definition not only leads to conflicting reports in the literature, but also is a major obstacle to research in the field. The recent consensus definition proposed by the Acute Dialysis Quality Initiative group and AKI Network (AKIN) has brought the risk, injury, failure, loss, and end-stage kidney (RIFLE) criteria and AKIN staging into position as the standard definition and diagnosis of this syndrome. The RIFLE criteria have been extensively validated in more than 250,000 patients worldwide.
- Subjects
ACUTE kidney failure; CREATININE; NOSOLOGY; INTENSIVE care units; DISEASE incidence; REPORTING of diseases; DIAGNOSIS
- Publication
European Critical Care & Emergency Medicine, 2010, Vol 2, p42
- ISSN
2042-7840
- Publication type
Article