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- Title
Diabetes and Metabolic Syndrome -- Risk Factors for Covid-19 (literature review).
- Authors
Nartikoeva M. I.; Dzampaeva Zh. V.; Takoeva E. A.
- Abstract
The COVID-19 pandemic is caused by severe acute respiratory syndrome 2 (SARS-CoV-2). The epidemiological situation, which has changed the past 2 years, dictates new rules of life. The nature of modern human nutrition has become a significant factor contributing to the occurrence of chronic diseases of the endocrine and cardiovascular systems (including obesity, type 2 diabetes mellitus, metabolic syndrome), each of them has become a risk factor of severe forms of COVID- 19. The aim of the study was to review scientific data on the risk factors of COVID-19, taking into account metabolic disorders that complicate the course of a new coronavirus infection, based on publications in the databases "Pubmed", "Google Scholar" for the period 2020-2021. Three main pathophysiological mechanisms linking metabolic disorders and COVID-19 have been identified: angiotensin converting enzyme dysregulation; liver dysfunction, chronic systemic inflammation with hypercoagulation. It has been shown that the risk observed among people with diabetes is also associated with insulin resistance, obesity, which can lead to an unfavorable outcome. It has been proven that diabetes and hyperglycemia are independent predictors of mortality and morbidity of COVID-19, and glycemic control can significantly improve the prognosis for the patient.
- Subjects
HYPERGLYCEMIA; CARDIOVASCULAR diseases; METABOLIC syndrome; TYPE 2 diabetes; ANGIOTENSIN converting enzyme
- Publication
Journal of International Dental & Medical Research, 2021, Vol 14, Issue 4, p1748
- ISSN
1309-100X
- Publication type
Case Study