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- Title
The serological and genetic basis of the cis-AB blood group in Korea.
- Authors
Cho, D.; Kim, S.-H.; Jeon, M.-J.; Choi, K.-L.; Kee, S.-J.; Shin, M.-G.; Shin, J.-H.; Suh, S.-P.; Yazer, M. H.; Ryang, D.-W.
- Abstract
The cis-AB blood group is rare, although relatively common amongst Koreans. The serological characteristics and genetic basis of Korean cis-AB blood donors were investigated. Polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP), designed to detect the cis-AB01 allele, was performed on 194 AB samples which demonstrated weak or unusual expression of either or both of the A or B antigens. Sixty cis-AB01 donors were identified. cis-AB01/O01 or O02 were the most common genotypes (36/60) detected only in A2B3 donors, and cis-AB01/B101 (nine of 60) was the least common genotype identified only in A2B donors. Surprisingly cis-AB01/A102 (15/60) was identified in a variety of phenotypes (A1B3, A1Bx or el, AintB3).
- Subjects
BLOOD; KOREANS; GENETICS; POLYMERASE chain reaction; BLOOD donors; ANTIGENS
- Publication
Vox Sanguinis, 2004, Vol 87, Issue 1, p41
- ISSN
0042-9007
- Publication type
Article
- DOI
10.1111/j.1423-0410.2004.00528.x