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- Title
Resection arthrodesis and osteoarticular allografts reconstruction after resection of primary bone tumors around the knee: Long‐term clinical outcomes and prognostic factors for failure of biological reconstruction.
- Authors
Wisanuyotin, Taweechok; Paholpak, Permsak; Sirichativapee, Winai; Kosuwon, Weerachai
- Abstract
Aim: The biological reconstruction of the knee with osteoarticular allografts and resection arthrodesis have been reported but there has not yet been a direct comparison between both these procedures. This study aimed to identify the prognostic factors that influence failure of biological reconstruction and compared the results between both procedures. Methods: Between 1994 and 2017, we performed 92 limb‐sparing procedures using resection arthrodesis (n = 53) and osteoarticular allograft reconstruction (n = 39) for the management of primary bone tumors around the knee. The minimum follow‐up time was 2 years in both groups. Results: The failure rate of reconstruction in the osteoarticular allograft and resection arthrodesis group was 48.7% and 39.6%, respectively (p = 0.75). The mean MSTS score in the osteoarticular allograft and resection arthrodesis group was 23.7 and 21.8, respectively (p = 0.01). The significant risk factor for failure after biological reconstruction was the administration of chemotherapy (p = 0.001; HR = 3.39; 95% CI, 1.60–7.17). Conclusion: Patients who underwent osteoarticular allograft had a better functional outcome than those who underwent resection arthrodesis reconstruction, but clinical outcomes between the groups were comparable. Chemotherapy is a significant adverse prognostic factor for failure of biological reconstruction.
- Subjects
ARTHRODESIS; PROGNOSIS; HOMOGRAFTS; TREATMENT effectiveness; KNEE; TUMORS; KIDNEY failure
- Publication
Asia Pacific Journal of Clinical Oncology, 2022, Vol 18, Issue 3, p240
- ISSN
1743-7555
- Publication type
Article
- DOI
10.1111/ajco.13607