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Characterization of HIV variants from paired Cerebrospinal fluid and Plasma samples in primary microglia and CD4<sup>+</sup> T-cells.
Published in:
Journal of NeuroVirology, 2024, v. 30, n. 4, p. 380, doi. 10.1007/s13365-024-01207-w
By:
- Gumbs, Stephanie B. H.;
- Stam, Arjen J.;
- Mudrikova, Tania;
- Schipper, Pauline J.;
- Hoepelman, Andy I. M.;
- van Ham, Petra M.;
- Borst, Anne L.;
- Hofstra, LMarije;
- Gharu, Lavina;
- van Wyk, Stephanie;
- Wilkinson, Eduan;
- de Witte, Lot D.;
- Wensing, Annemarie M. J.;
- Nijhuis, Monique
Publication type:
Article
Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses.
Published in:
Journal of NeuroVirology, 2022, v. 28, n. 1, p. 64, doi. 10.1007/s13365-021-01049-w
By:
- Gumbs, Stephanie B. H.;
- Kübler, Raphael;
- Gharu, Lavina;
- Schipper, Pauline J.;
- Borst, Anne L.;
- Snijders, Gijsje J. L. J.;
- Ormel, Paul R.;
- van Berlekom, Amber Berdenis;
- Wensing, Annemarie M. J.;
- de Witte, Lot D.;
- Nijhuis, Monique
Publication type:
Article
DNA methylation changes related to nutritional deprivation: a genome-wide analysis of population and in vitro data.
Published in:
Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0680-7
By:
- He, Yujie;
- de Witte, Lot D.;
- Houtepen, Lotte C.;
- Nispeling, Danny M.;
- Xu, Zhida;
- Yu, Qiong;
- Yu, Yaqin;
- Hol, Elly M.;
- Kahn, René S.;
- Boks, Marco P.
Publication type:
Article
A Sex-Dependent Association Between Doxycycline Use and Development of Schizophrenia.
Published in:
Schizophrenia Bulletin, 2023, v. 49, n. 4, p. 953, doi. 10.1093/schbul/sbad008
By:
- Witte, Lot D de;
- Laursen, Thomas Munk;
- Corcoran, Cheryl M;
- Kahn, René S;
- Birnbaum, Rebecca;
- Munk-Olsen, Trine;
- Bergink, Veerle
Publication type:
Article
Simvastatin Augmentation for Patients With Early-Phase Schizophrenia-Spectrum Disorders: A Double-Blind, Randomized Placebo-Controlled Trial.
Published in:
Schizophrenia Bulletin, 2021, v. 47, n. 4, p. 1108, doi. 10.1093/schbul/sbab010
By:
- Sommer, Iris E;
- Gangadin, Shiral S;
- Witte, Lot D de;
- Koops, Sanne;
- Baal, C van;
- Bahn, Sabine;
- Drexhage, Hemmo;
- Haren, N E M van;
- Veling, Wim;
- Bruggeman, R;
- Martens, Peter;
- Wiersma, Sybren;
- Veerman, Selene R T;
- Grootens, Koen P;
- Beveren, Nico van;
- Kahn, Rene S;
- Begemann, Marieke J H
Publication type:
Article
Synapse Pathology in Schizophrenia: A Meta-analysis of Postsynaptic Elements in Postmortem Brain Studies.
Published in:
Schizophrenia Bulletin, 2020, v. 46, n. 2, p. 374, doi. 10.1093/schbul/sbz060
By:
- Berlekom, Amber Berdenis van;
- Muflihah, Cita H;
- Snijders, Gijsje J L J;
- MacGillavry, Harold D;
- Middeldorp, Jinte;
- Hol, Elly M;
- Kahn, René S;
- Witte, Lot D de
Publication type:
Article
Efficacy of Anti-inflammatory Agents to Improve Symptoms in Patients With Schizophrenia: An Update.
Published in:
2014
By:
- Sommer, Iris E.;
- van Westrhenen, Roos;
- Begemann, Marieke J. H.;
- de Witte, Lot D.;
- Leucht, Stefan;
- Kahn, René S.
Publication type:
Journal Article
Efficacy of Anti-inflammatory Agents to Improve Symptoms in Patients With Schizophrenia: An Update.
Published in:
Schizophrenia Bulletin, 2014, v. 40, n. 1, p. 181, doi. 10.1093/schbul/sbt139
By:
- Sommer, Iris E.;
- van Westrhenen, Roos;
- Begemann, Marieke J. H.;
- de Witte, Lot D.;
- Leucht, Stefan;
- Kahn, René S.
Publication type:
Article
Atlas of genetic effects in human microglia transcriptome across brain regions, aging and disease pathologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.050942
By:
- Lopes, Katia P;
- Snijders, Gijsje J. L.;
- Humphrey, Jack;
- de Witte, Lot D.;
- Raj, Towfique
Publication type:
Article
Absence of N-Methyl-D-Aspartate Receptor IgG Autoantibodies in Schizophrenia: The Importance of Cross-Validation Studies.
Published in:
2015
By:
- de Witte, Lot D;
- Hoffmann, Carolin;
- van Mierlo, Hans C;
- Titulaer, Maarten J;
- Kahn, René S;
- Martinez-Martinez, Pilar;
- European Consortium of Autoimmune Mental Disorders (CAIMED)
Publication type:
Journal Article
Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression.
Published in:
Translational Psychiatry, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41398-020-00992-2
By:
- Böttcher, Chotima;
- Fernández-Zapata, Camila;
- Snijders, Gijsje J. L.;
- Schlickeiser, Stephan;
- Sneeboer, Marjolein A. M.;
- Kunkel, Desiree;
- De Witte, Lot D.;
- Priller, Josef
Publication type:
Article
Long-term effects of prenatal infection on the human brain: a prospective multimodal neuroimaging study.
Published in:
Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02597-x
By:
- Suleri, Anna;
- Cecil, Charlotte;
- Rommel, Anna-Sophie;
- Hillegers, Manon;
- White, Tonya;
- de Witte, Lot D.;
- Muetzel, Ryan L.;
- Bergink, Veerle
Publication type:
Article
Diagnostic model development for schizophrenia based on peripheral blood mononuclear cell subtype-specific expression of metabolic markers.
Published in:
Translational Psychiatry, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41398-022-02229-w
By:
- Zaki, Jihan K.;
- Lago, Santiago G.;
- Rustogi, Nitin;
- Gangadin, Shiral S.;
- Benacek, Jiri;
- van Rees, Geertje F.;
- Haenisch, Frieder;
- Broek, Jantine A.;
- Suarez-Pinilla, Paula;
- Ruland, Tillmann;
- Auyeung, Bonnie;
- Mikova, Olya;
- Kabacs, Nikolett;
- Arolt, Volker;
- Baron-Cohen, Simon;
- Crespo-Facorro, Benedicto;
- Drexhage, Hemmo A.;
- de Witte, Lot D.;
- Kahn, René S.;
- Sommer, Iris E.
Publication type:
Article
Cerebrospinal fluid abnormalities in first- and multi-episode schizophrenia-spectrum disorders: impact of clinical and demographical variables.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01751-7
By:
- Oviedo-Salcedo, Tatiana;
- Wagner, Elias;
- Campana, Mattia;
- Gagsteiger, Anna;
- Strube, Wolfgang;
- Eichhorn, Peter;
- Louiset, Marie-Luise;
- Luykx, Jurjen;
- de Witte, Lot D.;
- Kahn, René S.;
- Benros, Michael E.;
- Falkai, Peter;
- Hasan, Alkomiet
Publication type:
Article
The association between antibodies to neurotropic pathogens and bipolar disorder: A study in the Dutch Bipolar (DB) Cohort and meta-analysis.
Published in:
Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0636-x
By:
- Snijders, Gijsje J. L. J.;
- van Mierlo, Hans C.;
- Boks, Marco P.;
- Begemann, Marieke J. H.;
- Sutterland, Arjen L.;
- Litjens, Manja;
- Ophoff, Roel A.;
- Kahn, René S.;
- de Witte, Lot D.
Publication type:
Article
Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated.
Published in:
Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0490-x
By:
- Sneeboer, Marjolein A. M.;
- Snijders, Gijsje J. L. J.;
- Berdowski, Woutje M.;
- Fernández-Andreu, Alba;
- van Mierlo, Hans C.;
- Berdenis van Berlekom, Amber;
- Litjens, Manja;
- Kahn, René S.;
- Hol, Elly M.;
- de Witte, Lot D.
Publication type:
Article
Characterization of HIV-1 Infection in Microglia-Containing Human Cerebral Organoids.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 4, p. N.PAG, doi. 10.3390/v14040829
By:
- Gumbs, Stephanie B. H.;
- Berdenis van Berlekom, Amber;
- Kübler, Raphael;
- Schipper, Pauline J.;
- Gharu, Lavina;
- Boks, Marco P.;
- Ormel, Paul R.;
- Wensing, Annemarie M. J.;
- de Witte, Lot D.;
- Nijhuis, Monique
Publication type:
Article
Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.
Published in:
International Journal of Cancer, 2015, v. 137, n. 7, p. 1630, doi. 10.1002/ijc.29521
By:
- de Vrij, Jeroen;
- Maas, S.L. Niek;
- Kwappenberg, Kitty M.C.;
- Schnoor, Rosalie;
- Kleijn, Anne;
- Dekker, Lennard;
- Luider, Theo M.;
- de Witte, Lot D.;
- Litjens, Manja;
- van Strien, Miriam E.;
- Hol, Elly M.;
- Kroonen, Jerome;
- Robe, Pierre A.;
- Lamfers, Martine L.;
- Schilham, Marco W.;
- Broekman, Marike L.D.
Publication type:
Article
Shock and kill within the CNS: A promising HIV eradication approach?
Published in:
Journal of Leukocyte Biology, 2022, v. 112, n. 5, p. 1297, doi. 10.1002/JLB.5VMR0122-046RRR
By:
- Nühn, Marieke M.;
- Gumbs, Stephanie B. H.;
- Buchholtz, Ninée V. E. J.;
- Jannink, Lisanne M.;
- Gharu, Lavina;
- de Witte, Lot D.;
- Wensing, Annemarie M. J.;
- Lewin, Sharon R.;
- Nijhuis, Monique;
- Symons, Jori
Publication type:
Article
Microglia innately develop within cerebral organoids.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06684-2
By:
- Ormel, Paul R.;
- Vieira de Sá, Renata;
- van Bodegraven, Emma J.;
- Karst, Henk;
- Harschnitz, Oliver;
- Sneeboer, Marjolein A. M.;
- Johansen, Lill Eva;
- van Dijk, Roland E.;
- Scheefhals, Nicky;
- Berdenis van Berlekom, Amber;
- Ribes Martínez, Eduardo;
- Kling, Sandra;
- MacGillavry, Harold D.;
- van den Berg, Leonard H.;
- Kahn, René S.;
- Hol, Elly M.;
- de Witte, Lot D.;
- Pasterkamp, R. Jeroen
Publication type:
Article
Transcriptomic and morphological maturation of human astrocytes in cerebral organoids.
Published in:
Glia, 2024, v. 72, n. 2, p. 362, doi. 10.1002/glia.24479
By:
- Verkerke, Marloes;
- Berdenis van Berlekom, Amber;
- Donega, Vanessa;
- Vonk, Daniëlle;
- Sluijs, Jacqueline A.;
- Butt, Nayab F.;
- Kistemaker, Lois;
- de Witte, Lot D.;
- Pasterkamp, R. Jeroen;
- Middeldorp, Jinte;
- Hol, Elly M.
Publication type:
Article
Childhood Adversity Is Associated With Increased KITLG Methylation in Healthy Individuals but Not in Bipolar Disorder Patients.
Published in:
Frontiers in Psychiatry, 2019, p. N.PAG, doi. 10.3389/fpsyt.2018.00743
By:
- He, Yujie;
- Vinkers, Christiaan H.;
- Houtepen, Lotte C.;
- de Witte, Lot D.;
- Boks, Marco P.
Publication type:
Article
Childhood Adversity Is Associated With Increased KITLG Methylation in Healthy Individuals but Not in Bipolar Disorder Patients.
Published in:
Frontiers in Psychiatry, 2019, p. N.PAG, doi. 10.3389/fpsyt.2018.00743
By:
- He, Yujie;
- Vinkers, Christiaan H.;
- Houtepen, Lotte C.;
- de Witte, Lot D.;
- Boks, Marco P.
Publication type:
Article
The effect of SARS-CoV-2 infection and vaccination on Th17 and regulatory T cells in a pregnancy cohort in NYC.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1350288
By:
- Gigase, Frederieke A. J.;
- Graziani, Mara;
- Castro, Juliana;
- Lesseur, Corina;
- Rommel, Anna-Sophie;
- Flores, Tammy;
- Perez-Rodriguez, M. Mercedes;
- Dolan, Siobhan;
- Stone, Joanne;
- Janevic, Teresa;
- Lieb, Whitney;
- Bergink, Veerle;
- de Witte, Lot D.
Publication type:
Article
Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model.
Published in:
Nutrients, 2022, v. 14, n. 10, p. 2175, doi. 10.3390/nu14102175
By:
- Berdenis van Berlekom, Amber;
- Kübler, Raphael;
- Hoogeboom, Jeske W.;
- Vonk, Daniëlle;
- Sluijs, Jacqueline A.;
- Pasterkamp, R. Jeroen;
- Middeldorp, Jinte;
- Kraneveld, Aletta D.;
- Garssen, Johan;
- Kahn, René S.;
- Hol, Elly M.;
- de Witte, Lot D.;
- Boks, Marco P.
Publication type:
Article

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