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- Title
Management and Treatment of Patients with Chronic Hepatitis B: Towards Personalized Medicine.
- Authors
Colombatto, Piero; Coco, Barbara; Bonino, Ferruccio; Brunetto, Maurizia R.
- Abstract
The currently available antiviral treatments (Peg-Interferon-α and Nucleos(t)ide Analogues, NA) for chronic hepatitis B (CHB) achieve a functional cure (serum HBsAg and HDV-DNA clearance) of HBV infection in a limited number of patients. Nevertheless, the continuous pharmacological suppression of viral replication by NA halts liver disease progression lowering the risk of HCC development and improving the survival. In the near future, to fully exploit the potential of old and new drugs for HBV treatment a personalized approach to the patients will be required according to an accurate definition of their virologic, immunologic and clinical profile.
- Subjects
CHRONIC hepatitis B; INDIVIDUALIZED medicine; HEPATITIS B; VIRAL replication; DISEASE progression; OLDER patients
- Publication
Viruses (1999-4915), 2022, Vol 14, Issue 4, pN.PAG
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v14040701