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- Title
Asthma and atopic dermatitis in children born moderately and late preterm.
- Authors
Haataja, Paula; Korhonen, Päivi; Ojala, Riitta; Hirvonen, Mikko; Paassilta, Marita; Gissler, Mika; Luukkaala, Tiina; Tammela, Outi; Korhonen, Päivi
- Abstract
<bold>Unlabelled: </bold>This national register study aimed to evaluate the need of asthma medication reimbursement and hospitalization due to asthma and atopic dermatitis up to 7 years of age in moderately preterm (MP) (32-33 weeks) and late preterm (LP) (34-36 weeks) children compared to very preterm (VP) (<32 weeks) and term (≥37 weeks) children. Altogether, 1,018,302 children born in Finland between 1991 and 2008 were assessed. The MP and LP groups received asthma medication reimbursement more frequently than term controls (8.0 and 5.7 vs. 3.8 %), but less frequently than VP children (15.4 %). Hospitalization due to asthma was more common among MP (10.6 %) and LP (7.3 %) children than term children (4.8 %) but less common than in VP children (20.1 %). Hospitalization due to atopic dermatitis was more frequent among term (5.2 %) compared to MP (4.2 %) and LP (4.7 %) children. Male sex, maternal smoking, maternal diabetes, and ventilator therapy predicted asthma medication in the MP and/or LP children.<bold>Conclusion: </bold>MP and LP children seem to need medication and hospitalization for asthma more often than term controls but less frequently than VP children followed by 7 years of age. Hospitalization due to atopic dermatitis becomes more common with increasing gestational age.<bold>What Is Known: </bold>• MP and LP infants have an increased risk for early respiratory morbidity and to asthma. • Less is known on the occurrence of atopic dermatitis in this patient group. What is New: • Medication and hospital care due to asthma were more frequent in school-aged MP and LP than in term infants. Male sex, maternal smoking, maternal diabetes and ventilator therapy predicted asthma. • Hospitalization due to atopic dermatitis became more common with increasing gestational age.
- Subjects
FINLAND; ATOPIC dermatitis; ASTHMA in children; PREMATURE infant diseases; HOSPITAL care; PREGNANT women; WOMEN'S tobacco use; ASTHMA treatment; ATOPIC dermatitis treatment; ASTHMA; GESTATIONAL age; PREMATURE infants; MOTHERS; ACQUISITION of data; DISEASE prevalence
- Publication
European Journal of Pediatrics, 2016, Vol 175, Issue 6, p799
- ISSN
0340-6199
- Publication type
journal article
- DOI
10.1007/s00431-016-2708-8