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- Title
Paraneoplastic syndromes in ganglioneuroblastoma: contrasting symptoms of constipation and diarrhoea.
- Authors
Wildhaber, Barbara; Niggli, Felix; Bergsträsser, Eva; Stallmach, Thomas; Sacher, Peter
- Abstract
.A paraneoplastic syndrome is occasionally the first clinical symptom seen with tumours. We report on two children who initially presented with paraneoplastic syndromes due to ganglioneuroblastomas: the first with severe watery diarrhoea caused by a ganglioneuroma producing vasoactive intestinal peptide, the second with non-treatable constipation, caused by ganglioneuroma-produced anti-neuronal nuclear antibodies. Conclusion: Either severe diarrhoea or chronic constipation may represent rare paraneoplastic syndromes in ganglioneuroblastomas.
- Subjects
PARANEOPLASTIC syndromes; NEUROBLASTOMA; TUMORS in children
- Publication
European Journal of Pediatrics, 2003, Vol 162, Issue 7/8, p511
- ISSN
0340-6199
- Publication type
Article
- DOI
10.1007/s00431-003-1212-0