We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Plasma concentrations of granulocyte-macrophage colony-stimulating factor and interleukin-6 in septic and healthy preterms.
- Authors
Kantar, M.; Kültürsay, N.; Kütükcüler, N.; Akisü, M.; Çetingül, N.; Çaglayan, S.; Kültürsay, N; Kütükçüler, N; Akisü, M; Cetingül, N; Caglayan, S
- Abstract
<bold>Unlabelled: </bold>Plasma granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-6 (IL-6) concentrations were determined in 21 preterm infants with sepsis and nine healthy preterm neonates of the same postnatal age at sampling. Plasma GM-CSF levels were elevated at diagnosis in the septic preterms as compared to the healthy preterms (P = 0.01), but did not differ significantly on recovery. IL-6 levels were also elevated markedly at diagnosis (P = 0.0003), but decreased to normal on recovery as compared to the healthy preterm infants. GM-CSF levels were more prominent in septic preterms with neutropenia than those of non-neutropenic infants (P = 0.03).<bold>Conclusion: </bold>Preterm infants can produce high levels of granulocyte-macrophage colony-stimulating factor and interleukin-6 in response to bacterial sepsis.
- Subjects
BLOOD plasma; GRANULOCYTE-macrophage colony-stimulating factor; INTERLEUKINS; SEPSIS; PREMATURE infants; PREMATURE infant diseases; KLEBSIELLA; PNEUMONIA; KLEBSIELLA infections
- Publication
European Journal of Pediatrics, 2000, Vol 159, Issue 3, p156
- ISSN
0340-6199
- Publication type
journal article
- DOI
10.1007/s004310050041