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- Title
Drug-Induced Hypersensitivity Syndrome Followed by Subacute Thyroiditis.
- Authors
Sato, Mika; Mizuno, Yuki; Matsuyama, Kanako; Shu, En; Kanoh, Hiroyuki; Suwa, Tetsuya; Seishima, Mariko
- Abstract
Drug-induced hypersensitivity syndrome (DIHS) is a severe multiorgan system adverse drug reaction with reactivation of human herpesviruses (HHVs) such as HHV-6, HHV-7, cytomegalovirus (CMV) and Epstein-Barr virus. Various complications, including autoimmune diseases, sometimes appear during the course of DIHS. We report a case of salazosulfapyridine-induced DIHS associated with HHV-6 reactivation. Two and a half months after the onset of DIHS, subacute thyroiditis occurred, possibly associated with CMV reactivation. Prednisolone (20 mg/day) was effective for subacute thyroiditis. Long-term follow-up is needed in patients with DIHS because of the possible onset of autoimmune diseases. © 2015 S. Karger AG, Basel
- Subjects
DRESS syndrome; CYTOMEGALOVIRUSES; AUTOIMMUNE thyroiditis; THYROIDITIS; EPSTEIN-Barr virus; HERPESVIRUSES
- Publication
Case Reports in Dermatology, 2015, Vol 7, Issue 2, p161
- ISSN
1662-6567
- Publication type
Article
- DOI
10.1159/000437251