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- Title
Cranial neuropathy, polyneuropathy and thrombocytopenia with Epstein-Barr virus infection.
- Authors
Connolly, Mary; Junker, Anne K.; Chan, Ka Wah; Farrell, Kevin; Connolly, M; Junker, A K; Chan, K W; Farrell, K
- Abstract
Neurological involvement is an uncommon complication of Epstein-Barr virus infection, and the long incubation period may complicate the diagnosis. A 15-year-old boy is described with Epstein-Barr virus infection complicated by prolonged life-threatening thrombocytopenia, cranial neuropathy and peripheral sensorimotor neuropathy. The abnormal platelet count was unresponsive to multiple-drug therapy and splenectomy, but normalized 13 months after presentation. Neurological recovery was slow; the patient continues to have a mild peripheral sensorimotor neuropathy three years after the onset of the illness. Infection with Epstein-Barr virus should be considered in patients with acute neurological problems associated with thrombocytopenia. Measurement of antibodies to individual Epstein-Barr virus proteins facilitates the diagnosis of Epstein-Barr virus infection.
- Publication
Developmental Medicine & Child Neurology, 1994, Vol 36, Issue 11, p1010
- ISSN
0012-1622
- Publication type
journal article
- DOI
10.1111/j.1469-8749.1994.tb11797.x