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A novel method to generate single-cell-derived cancer-associated fibroblast clones.
Published in:
Journal of Cancer Research & Clinical Oncology, 2017, v. 143, n. 8, p. 1409, doi. 10.1007/s00432-017-2409-3
By:
- Hashimoto, Hiroko;
- Suda, Yoshitaka;
- Miyashita, Tomoyuki;
- Ochiai, Atsushi;
- Tsuboi, Masahiro;
- Masutomi, Kenkichi;
- Kiyono, Tohru;
- Ishii, Genichiro
Publication type:
Article
Clonal heterogeneity in osteogenic potential of lung cancer-associated fibroblasts: promotional effect of osteogenic progenitor cells on cancer cell migration.
Published in:
Journal of Cancer Research & Clinical Oncology, 2016, v. 142, n. 7, p. 1487, doi. 10.1007/s00432-016-2171-y
By:
- Suda, Yoshitaka;
- Neri, Shinya;
- Hashimoto, Hiroko;
- Higuchi, Youichi;
- Ishibashi, Masayuki;
- Sugano, Masato;
- Masutomi, Kenkichi;
- Tsuboi, Masahiro;
- Ochiai, Atsushi;
- Ishii, Genichiro
Publication type:
Article
Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts.
Published in:
Journal of Cancer Research & Clinical Oncology, 2016, v. 142, n. 2, p. 437, doi. 10.1007/s00432-015-2046-7
By:
- Neri, Shinya;
- Hashimoto, Hiroko;
- Kii, Hiroaki;
- Watanabe, Hirotada;
- Masutomi, Kenkichi;
- Kuwata, Takeshi;
- Date, Hiroshi;
- Tsuboi, Masahiro;
- Goto, Koichi;
- Ochiai, Atsushi;
- Ishii, Genichiro
Publication type:
Article
Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 18, p. 4595, doi. 10.3390/ijms20184595
By:
- Maishi, Nako;
- Kikuchi, Hiroshi;
- Sato, Masumi;
- Nagao-Kitamoto, Hiroko;
- Annan, Dorcas A.;
- Baba, Shogo;
- Hojo, Takayuki;
- Yanagiya, Misa;
- Ohba, Yusuke;
- Ishii, Genichiro;
- Masutomi, Kenkichi;
- Shinohara, Nobuo;
- Hida, Yasuhiro;
- Hida, Kyoko
Publication type:
Article
Telomerase Reverse Transcriptase Regulates microRNAs.
Published in:
International Journal of Molecular Sciences, 2015, v. 16, n. 1, p. 1192, doi. 10.3390/ijms16011192
By:
- Lassmann, Timo;
- Yoshiko Maida;
- Yasuhiro Tomaru;
- Mami Yasukawa;
- Yoshinari Ando;
- Miki Kojima;
- Kasim, Vivi;
- Simon, Christophe;
- Daub, Carsten O.;
- Carninci, Piero;
- Yoshihide Hayashizaki;
- Kenkichi Masutomi
Publication type:
Article
Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells.
Published in:
International Journal of Molecular Sciences, 2013, v. 14, n. 5, p. 9305, doi. 10.3390/ijms14059305
By:
- Maida, Yoshiko;
- Kyo, Satoru;
- Lassmann, Timo;
- Hayashizaki, Yoshihide;
- Masutomi, Kenkichi
Publication type:
Article
Kinetics of DNA replication and telomerase reaction at a single-seeded telomere in human cells.
Published in:
Genes to Cells, 2012, v. 17, n. 3, p. 186, doi. 10.1111/j.1365-2443.2012.01581.x
By:
- Hirai, Yugo;
- Masutomi, Kenkichi;
- Ishikawa, Fuyuki
Publication type:
Article
Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2.
Published in:
Virology Journal, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12985-022-01948-2
By:
- Machitani, Mitsuhiro;
- Takei, Junko;
- Kaneko, Mika K.;
- Ueki, Saori;
- Ohashi, Hirofumi;
- Watashi, Koichi;
- Kato, Yukinari;
- Masutomi, Kenkichi
Publication type:
Article
Two-step cleavage of hairpin RNA with 5' overhangs by human DICER.
Published in:
BMC Molecular Biology, 2011, v. 12, n. 1, p. 1, doi. 10.1186/1471-2199-12-6
By:
- Ando, Yoshinari;
- Maida, Yoshiko;
- Morinaga, Ayako;
- Burroughs, Alexander M;
- Kimura, Ryuichiro;
- Chiba, Joe;
- Suzuki, Harukazu;
- Masutomi, Kenkichi;
- Hayashizaki, Yoshihide
Publication type:
Article
Two-step cleavage of hairpin RNA with 5' overhangs by human DICER.
Published in:
BMC Molecular Biology, 2011, v. 12, n. 1, p. 6, doi. 10.1186/1471-2199-12-6
By:
- Ando, Yoshinari;
- Maida, Yoshiko;
- Morinaga, Ayako;
- Burroughs, Alexander M.;
- Kimura, Ryuichiro;
- Chiba, Joe;
- Suzuki, Harukazu;
- Masutomi, Kenkichi;
- Hayashizaki, Yoshihide
Publication type:
Article
CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.
Published in:
Scientific Reports, 2017, p. 46662, doi. 10.1038/srep46662
By:
- Ishibashi, Masayuki;
- Neri, Shinya;
- Hashimoto, Hiroko;
- Miyashita, Tomoyuki;
- Yoshida, Tatsuya;
- Nakamura, Yuka;
- Udagawa, Hibiki;
- Kirita, Keisuke;
- Matsumoto, Shingo;
- Umemura, Shigeki;
- Yoh, Kiyotaka;
- Niho, Seiji;
- Tsuboi, Masahiro;
- Masutomi, Kenkichi;
- Goto, Koichi;
- Ochiai, Atsushi;
- Ishii, Genichiro
Publication type:
Article
Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112438
By:
- Yamaguchi, Satoko;
- Maida, Yoshiko;
- Yasukawa, Mami;
- Kato, Tomoyasu;
- Yoshida, Masayuki;
- Masutomi, Kenkichi
Publication type:
Article
RMRP Is a Non-Coding RNA Essential for Early Murine Development.
Published in:
PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026270
By:
- Rosenbluh, Joseph;
- Nijhawan, Deepak;
- Chen, Zhao;
- Wong, Kwok-Kin;
- Masutomi, Kenkichi;
- Hahn, William C.
Publication type:
Article
A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis.
Published in:
PLoS ONE, 2008, v. 3, n. 10, p. 1, doi. 10.1371/journal.pone.0003364
By:
- Imamura, Shintaro;
- Uchiyama, Junzo;
- Koshimizu, Eriko;
- Hanai, Jun-ichi;
- Raftopoulou, Christina;
- Murphey, Ryan D.;
- Bayliss, Peter E.;
- Imai, Yoichi;
- Burns, Caroline Erter;
- Masutomi, Kenkichi;
- Gagos, Sarantis;
- Zon, Leonard I.;
- Roberts, Thomas M.;
- Kishi, Shuji
Publication type:
Article
Identification of serum anti-human telomerase reverse transcriptase (hTERT) auto-antibodies during progression to hepatocellular carcinoma.
Published in:
Oncogene, 2002, v. 21, n. 38, p. 5946, doi. 10.1038/sj.onc.1205788
By:
- Masutomi, Kenkichi;
- Kaneko, Shuichi;
- Yasukawa, Mami;
- Arai, Kuniaki;
- Murakami, Seishi;
- Kobayashi, Kenichi
Publication type:
Article
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA.
Published in:
Nature, 2009, v. 461, n. 7261, p. 230, doi. 10.1038/nature08283
By:
- Maida, Yoshiko;
- Yasukawa, Mami;
- Furuuchi, Miho;
- Lassmann, Timo;
- Possemato, Richard;
- Okamoto, Naoko;
- Kasim, Vivi;
- Hayashizaki, Yoshihide;
- Hahn, William C.;
- Masutomi, Kenkichi
Publication type:
Article
Elevated TERT Expression in TERT-Wildtype Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody.
Published in:
BioMed Research International, 2018, v. 2018, p. 1, doi. 10.1155/2018/7945845
By:
- Masui, Kenta;
- Komori, Takashi;
- Kato, Yukinari;
- Masutomi, Kenkichi;
- Ichimura, Koichi;
- Ogasawara, Satoshi;
- Kaneko, Mika K.;
- Oki, Hiroharu;
- Suzuki, Hiroyoshi;
- Nitta, Masayuki;
- Maruyama, Takashi;
- Muragaki, Yoshihiro;
- Kawamata, Takakazu;
- Sawada, Tatsuo;
- Shibata, Noriyuki
Publication type:
Article
Analysis of telomeric single-strand overhang length in human endometrial cancers
Published in:
FEBS Letters, 2005, v. 579, n. 13, p. 2959, doi. 10.1016/j.febslet.2005.04.021
By:
- Hashimoto, Manabu;
- Kyo, Satoru;
- Masutomi, Kenkichi;
- Maida, Yoshiko;
- Sakaguchi, Junko;
- Mizumoto, Yasunari;
- Nakamura, Mitsuhiro;
- Hahn, William C.;
- Inoue, Masaki
Publication type:
Article
Nucleostemin expression in invasive breast cancer.
Published in:
BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-215
By:
- Takayuki Kobayashi;
- Kenkichi Masutomi;
- Kenji Tamura;
- Tomoyuki Moriya;
- Tamio Yamasaki;
- Yasuhiro Fujiwara;
- Shunji Takahashi;
- Junji Yamamoto;
- Hitoshi Tsuda
Publication type:
Article
Eribulin prolongs survival in an orthotopic xenograft mouse model of malignant meningioma.
Published in:
Cancer Science, 2022, v. 113, n. 2, p. 697, doi. 10.1111/cas.15221
By:
- Nakano, Tomoyuki;
- Fujimoto, Kenji;
- Tomiyama, Arata;
- Takahashi, Masamichi;
- Achiha, Takamune;
- Arita, Hideyuki;
- Kawauchi, Daisuke;
- Yasukawa, Mami;
- Masutomi, Kenkichi;
- Kondo, Akihide;
- Narita, Yoshitaka;
- Maehara, Taketoshi;
- Ichimura, Koichi
Publication type:
Article
RNA‐dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID‐19.
Published in:
Cancer Science, 2020, v. 111, n. 11, p. 3976, doi. 10.1111/cas.14618
By:
- Machitani, Mitsuhiro;
- Yasukawa, Mami;
- Nakashima, Jotaro;
- Furuichi, Yasuhiro;
- Masutomi, Kenkichi
Publication type:
Article
Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts.
Published in:
Cancer Science, 2019, v. 110, n. 7, p. 2247, doi. 10.1111/cas.14067
By:
- Takahashi, Masamichi;
- Miki, Shunichiro;
- Fujimoto, Kenji;
- Fukuoka, Kohei;
- Matsushita, Yuko;
- Maida, Yoshiko;
- Yasukawa, Mami;
- Hayashi, Mitsuhiro;
- Shinkyo, Raku;
- Kikuchi, Kiyomi;
- Mukasa, Akitake;
- Nishikawa, Ryo;
- Tamura, Kenji;
- Narita, Yoshitaka;
- Hamada, Akinobu;
- Masutomi, Kenkichi;
- Ichimura, Koichi
Publication type:
Article
Concomitant administration of radiation with eribulin improves the survival of mice harboring intracerebral glioblastoma.
Published in:
Cancer Science, 2018, v. 109, n. 7, p. 2275, doi. 10.1111/cas.13637
By:
- Miki, Shunichiro;
- Imamichi, Shoji;
- Fujimori, Hiroaki;
- Tomiyama, Arata;
- Fujimoto, Kenji;
- Satomi, Kaishi;
- Matsushita, Yuko;
- Matsuzaki, Sanae;
- Takahashi, Masamichi;
- Ishikawa, Eiichi;
- Yamamoto, Tetsuya;
- Matsumura, Akira;
- Mukasa, Akitake;
- Nishikawa, Ryo;
- Masutomi, Kenkichi;
- Narita, Yoshitaka;
- Masutani, Mitsuko;
- Ichimura, Koichi
Publication type:
Article
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase.
Published in:
Cancer Science, 2015, v. 106, n. 11, p. 1486, doi. 10.1111/cas.12806
By:
- Maida, Yoshiko;
- Masutomi, Kenkichi
Publication type:
Article
Efficacy of everolimus, a novel m TOR inhibitor, against basal-like triple-negative breast cancer cells.
Published in:
Cancer Science, 2012, v. 103, n. 9, p. 1665, doi. 10.1111/j.1349-7006.2012.02359.x
By:
- Yunokawa, Mayu;
- Koizumi, Fumiaki;
- Kitamura, Yuka;
- Katanasaka, Yasufumi;
- Okamoto, Naoko;
- Kodaira, Makoto;
- Yonemori, Kan;
- Shimizu, Chikako;
- Ando, Masashi;
- Masutomi, Kenkichi;
- Yoshida, Teruhiko;
- Fujiwara, Yasuhiro;
- Tamura, Kenji
Publication type:
Article
Nucleostemin and TWIST as predictive markers for recurrence after neoadjuvant chemotherapy for esophageal carcinoma.
Published in:
Cancer Science, 2012, v. 103, n. 2, p. 233, doi. 10.1111/j.1349-7006.2011.02142.x
By:
- Nakajima, Takako E.;
- Yoshida, Hiroshi;
- Okamoto, Naoko;
- Nagashima, Kengo;
- Taniguchi, Hirokazu;
- Yamada, Yasuhide;
- Shimoda, Tadakazu;
- Masutomi, Kenkichi
Publication type:
Article
Association of longer telomere length in cancer cells and cancer-associated fibroblasts with worse prognosis.
Published in:
JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 2, p. 208, doi. 10.1093/jnci/djac226
By:
- Matsuda, Yoko;
- Ye, Juanjuan;
- Yamakawa, Keiko;
- Mukai, Yuri;
- Azuma, Kazuki;
- Wu, Linxuan;
- Masutomi, Kenkichi;
- Yamashita, Taro;
- Daigo, Yataro;
- Miyagi, Yohei;
- Yokose, Tomoyuki;
- Oshima, Takashi;
- Ito, Hiroyuki;
- Morinaga, Soichiro;
- Kishida, Takeshi;
- Minamoto, Toshinari;
- Kojima, Motohiro;
- Kaneko, Shuichi;
- Haba, Reiji;
- Kontani, Keiichi
Publication type:
Article
CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15289-7
By:
- Yasukawa, Mami;
- Ando, Yoshinari;
- Yamashita, Taro;
- Matsuda, Yoko;
- Shoji, Shisako;
- Morioka, Masaki Suimye;
- Kawaji, Hideya;
- Shiozawa, Kumiko;
- Machitani, Mitsuhiro;
- Abe, Takaya;
- Yamada, Shinji;
- Kaneko, Mika K.;
- Kato, Yukinari;
- Furuta, Yasuhide;
- Kondo, Tadashi;
- Shirouzu, Mikako;
- Hayashizaki, Yoshihide;
- Kaneko, Shuichi;
- Masutomi, Kenkichi
Publication type:
Article
Nucleostemin expression in invasive breast cancer.
Published in:
2014
By:
- Kobayashi, Takayuki;
- Masutomi, Kenkichi;
- Tamura, Kenji;
- Moriya, Tomoyuki;
- Yamasaki, Tamio;
- Fujiwara, Yasuhiro;
- Takahashi, Shunji;
- Yamamoto, Junji;
- Tsuda, Hitoshi
Publication type:
journal article
RNA-dependent RNA polymerases in RNA silencing.
Published in:
Biological Chemistry, 2011, v. 392, n. 4, p. 299, doi. 10.1515/BC.2011.035
By:
- Maida, Yoshiko;
- Masutomi, Kenkichi
Publication type:
Article

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