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- Title
Ci-POU-IVexpression identifies PNS neurons in embryos and larvae of the ascidianCiona intestinalis.
- Authors
Candiani, Simona; Pennati, Roberta; Oliveri, Diana; Locascio, Annamaria; Branno, Margherita; Castagnola, Patrizio; Pestarino, Mario; De Bernardi, Fiorenza
- Abstract
Several lines of evidence suggest that members of the POU domain gene family may regulate invertebrate and vertebrate neurogenesis. In particular, POU IV genes appear to be neural genes involved in differentiation of sensory neurons, as demonstrated in mollusc,Drosophila,Caenorhabditis elegansand vertebrates. In the present work, we describe the developmental expression of a homologue of POU IV genes,Ci-POU-IV, in the ascidianCiona intestinalis.Ci-POU-IVis expressed in the precursor cells of the neural system during development and in the neural system of the larva. In particular, transcripts are prevalent in the peripheral nervous system (PNS), with expression in the central nervous system (CNS) restricted to the posterior sensory vesicle. Therefore, the evolution of a complex sensory system seems to be under the control of a common genetic mechanism.
- Subjects
DEVELOPMENTAL neurobiology; GENES; HEREDITY; MOLECULAR genetics; SENSORY neurons; PERIPHERAL nervous system; CENTRAL nervous system
- Publication
Development Genes & Evolution, 2005, Vol 215, Issue 1, p41
- ISSN
0949-944X
- Publication type
Article
- DOI
10.1007/s00427-004-0444-y