We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Cardioinhibitory Properties of Potato Glycoalkaloids in Beetles.
- Authors
Marciniak, Paweł; Adamski, Zbigniew; Bednarz, Paweł; Slocinska, Malgorzata; Ziemnicki, Kazimierz; Lelario, Filomena; Scrano, Laura; Bufo, Sabino A.
- Abstract
The semi-isolated heart bioassay was used to evaluate the effect of glycoalkaloids extracted from potato leaves on the heart contractile activity of three beetle species Zophobas atratus, Tenebrio molitor and Leptinotarsa decemlineata. The dose–response curves indicated species specific action of tested substances. Application of glycoalkaloids on the continuously perfused Z. atratus heart inhibited progressively frequency contractions; higher concentrations exerted short and reversible cardiac arrests. In the rest two beetle species tested glycoalkaloids caused no cardiotropic effect. In vivo bioassay with 1 day old Z. atratus pupae showed that the extract induces a negative inotropic effect on the heart.
- Subjects
BIOLOGICAL assay; COLORADO potato beetle; BEETLES; CARDIAC arrest; HEART failure; INSECT development; PESTICIDES
- Publication
Bulletin of Environmental Contamination & Toxicology, 2010, Vol 84, Issue 2, p153
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-009-9921-3