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- Title
One-Year Follow-Up After Single Procedure Cryoballoon Ablation: A Comparison Between the First and Second Generation Balloon.
- Authors
GIOVANNI, GIACOMO DI; WAUTERS, KRISTEL; CHIERCHIA, GIAN‐BATTISTA; SIEIRA, JUAN; LEVINSTEIN, MOISES; CONTE, GIULIO; DE ASMUNDIS, CARLO; BALTOGIANNIS, GIANNIS; SAITOH, YUKIO; CICONTE, GIUSEPPE; JULIA, JUSTO; MUGNAI, GIACOMO; IRFAN, GHAZALA; BRUGADA, PEDRO
- Abstract
A Comparison Between the First and Second Generation Balloon Background With respect to the first generation Cryoballoon (CB), the second generation (Cryoballoon Advance [CB-A], Medtronic, Minneapolis, MN, USA) was designed with technical modifications resulting in a larger and more uniform zone of freezing on the balloon's surface aiming at procedural outcome improvement in the setting of atrial fibrillation (AF) ablation. However, a comparison between both technologies on a midterm follow-up is missing in today's literature. Methods A total of 100 patients (the last 50 patients with the first generation CB and the first 50 patients with the second generation CB-A upon its inception in our center) having undergone a single CB ablation for paroxysmal AF (PAF) and having completed a 12-month follow-up, were consecutively included in our study. Freedom from AF off-antiarrhythmic drugs (AADs) after a single procedure was 78% (39/50) in CB-A and 58% (29/50) in the CB group (P = 0.03) during the whole follow-up duration. Considering a blanking period of 3 months, freedom from AF off-AAD was achieved in 84% (42/50) in CB-A, while 66% (33/50) were free from recurrence in the CB group (P = 0.038). Right phrenic nerve palsy (PNP) occurred in 8 patients (16%) in CB-A group and in 4 patients (8%) in the CB group. Conclusion Freedom from AF on 12 months follow-up was significantly higher in the CB-A group with respect to the first generation device. The most frequent complication observed was PNP.
- Subjects
CRYOSURGERY; PULMONARY veins; CATHETER ablation; ATRIAL fibrillation; CHI-squared test; COMPARATIVE studies; FISHER exact test; LONGITUDINAL method; HEALTH outcome assessment; SURGICAL complications; T-test (Statistics); U-statistics; DISEASE relapse; TREATMENT effectiveness; DATA analysis software; DESCRIPTIVE statistics; KAPLAN-Meier estimator; LOG-rank test; EQUIPMENT &; supplies; SURGERY
- Publication
Journal of Cardiovascular Electrophysiology, 2014, Vol 25, Issue 8, p834
- ISSN
1045-3873
- Publication type
Article
- DOI
10.1111/jce.12409