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- Title
Association between atopy and recurrent vaginal candidiasis.
- Authors
Neves, N. A.; Carvalho, L. P.; De Oliveira, M. A. M.; Giraldo, P. C.; Bacellar, O.; Cruz, Á. A.; Carvalho, E. M.
- Abstract
To determine whether there is an association between atopy and recurrent vaginal candidiasis (RVC) and to evaluate the type-2 immune response in patients with RVC. Evaluation of immediate hypersensitivity skin tests to aeroallergens, measurement of total IgE and Candida albicans specific IgE and levels of IL-5 in 44 women with RVC and 26 with sporadic vaginal candidiasis (SVC). Statistical analyses were performed by Mann–Whitney test and χ2 test with Yates correction. History of atopy (68%) and positive skin test (42%) were higher ( P < 0·05) in RVC than in patients with SVC. No significant difference was found in total IgE, C. albicans specific IgE and IL-5 levels. There was a strong association between atopy and RVC, but type-2 immune response to C. albicans antigen was absent or similar in the two groups of patients.
- Subjects
CANDIDIASIS; VAGINAL diseases; IMMUNE response; ALLERGIES; SKIN tests; CANDIDA albicans
- Publication
Clinical & Experimental Immunology, 2005, Vol 142, Issue 1, p167
- ISSN
0009-9104
- Publication type
Article
- DOI
10.1111/j.1365-2249.2005.02891.x