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- Title
Brain tumor and Gliadel wafer treatment.
- Authors
Panigrahi, M.; Das, P. K.; Parikh, P. M.
- Abstract
Glioblastoma is a rapidly progressive and extremely fatal form of brain tumor with poor prognosis. It is the most common type of primary brain tumor. Even with the most aggressive conventional treatment that comprises surgery followed by radiotherapy and chemotherapy, most patients die within a year of diagnosis. Developments in molecular and cell biology have led to better understanding of tumor development, leading to novel treatment strategies including biological therapy and immunotherapy to combat the deadly disease. Targeted drug delivery strategies to circumvent the bloodbrain barrier have shown efficiency in clinical trials. Gliadel wafer is a new approach to the treatment of glioblastoma, which involves controlled release delivery of carmustine from biodegradable polymer wafers. It has shown promising results and provides a silver lining for glioblastoma patients.
- Subjects
GLIOBLASTOMA multiforme treatment; BRAIN tumors; DRUG therapy; IMMUNOTHERAPY; CLINICAL trials
- Publication
Indian Journal of Cancer, 2011, Vol 48, Issue 1, p11
- ISSN
0019-509X
- Publication type
Article
- DOI
10.4103/0019-509X.76623